Justin Xavier Moore, PhD, MPHJustin Xavier Moore, PhD, MPH

Assistant Professor

Cancer Prevention, Control, & Population Health Program

Institute of Public and Preventive Health

Medical College of Georgia at Augusta University

Research Summary

Dr. Moore is an epidemiologist with vast skills in biostatistics, epidemiology, database design, geographic information systems (GIS), mediation analysis, and cancer prevention and control. Dr. Moore serves as an Assistant Professor in the Cancer Prevention, Control, & Population Health Program, Department of Medicine; and the Institute of Public and Preventive Health at the Medical College of Georgia at Augusta University. Dr. Moore’s research explores the intersection between race (including effects of racism) and place (social and built environment) on various health outcomes including cancer and infectious diseases. Dr. Moore’s work delineated that place matters for African American, Hispanic, and rural populations characterized by hot spots of excess mortality from breast cancer, lung cancer, early-onset colorectal cancer, sepsis, and COVID-19. Dr. Moore’s current research interests lie in understanding the effects of race and place on determinants of breast cancer including breast cancer screening, mammographic density, life-course stress, and DNA methylation.

Contact Us

Justin Xavier Moore, PhD, MPH

Health Sciences Campus

Georgia Cancer Center - M. Bert Storey Research Building

CN-2135

(706) 721-4621

jusmoore@augusta.edu

Research Team

photo of Sydney Andrzejak, MS

Sydney Andrzejak, MS

  • Community Outreach Coordinator
photo of Ryan Johnson, MPH

Ryan Johnson, MPH

  • Student Assistant
photo of Camelia Malkami, BA

Camelia Malkami, BA

  • Student Assistant

Research Projects & Interests

Racial and Socioeconomic Disparities in Cancer Outcomes

Dr. Moore has focused on examining health disparities (including racial, socio-economic, rural, and geographic) in cancer outcomes within the United States. Racial minorities and socioeconomically disadvantaged populations often face substantial barriers to adequate healthcare, greatly affecting quality of life and mortality. We have examined the influence of personal and neighborhood level, socioeconomic factors, and availability to healthcare resources in relation to racial differences in survival and treatment of various cancers (including breast and colorectal).

  • Dr. Moore currently serves as principal investigator of the Geographic and Racial Disparities in Mammography Screening and Barriers to Receiving Care study funded by the National Institutes of Health, National Institute on Minority Health and Health Disparities (K01MD015304-01). Link to NIH report here: Justin Moore K01
  • Dr. Moore serves a Co-Investigator for the Impacting Cancer Health Disparities and Facilitating Cancer Health Equity in Breast, Multiple Myeloma, and Prostate Cancers in Underserved and Minority Populations: The cancer-Community Awareness Access Research & Education II (c-Care II) Initiative funded by Bristol Meyers Squibb Foundation.
  • Dr. Moore serves as a Co-Investigator for the Cancer Health Awareness through screeNinG and Education (CHANGE) project funded through the American Cancer Society & Pfizer.

Racial and Geographic Disparities in COVID-19

The disease burden COVID-19 require novel approaches to identify most troubled areas geographically (i.e., hot spots), vulnerable populations, and associated risk factors in effort of mitigating the long-term risks and effects resulting from COVID-19 and eliminating future risks for unaffected communities. Dr. Moore’s research has observed possible rural-urban differences in COVID-19 incidence mortality, which may be partially explained by community level factors such as access to healthcare, number of physicians, number of intensive care unit beds, and personal level factors such as African American race. In addition, Dr. Moore has worked with numerous community leaders and organizations to help mitigate COVID-19 disparities within the Central Savannah River Area through community engaged programming to disseminate from COVID-19 tests, personal protective equipment, COVID-19 health information, COVID-19 vaccine information, health resources, and vaccine clinics.

  • Dr. Moore serves as a Scientist Partner for the Cultivating Community Co-Researchers to Build Capacity for PCOR for COVID-19 project funded through the Patient-Centered Outcomes Research Institute (PCORI).

Health Disparities and Long-Term Risk Factors for Sepsis

Dr. Moore utilized data from nationally representative cohorts and national mortality data to determine the risk factors for community-acquired sepsis. Sepsis, or infection with systemic inflammation, is a large and growing problem, leading to over 750,000 hospitalizations annually in the US. Dr. Moore has explored relationships between various characteristics measured at baseline and associated with the development of sepsis across a ten-year observation period. Dr. Moore’s research represented a new conceptualization of sepsis by approaching it as a preventable occurrence with potentially modifiable risk factors.

Selected Publications

Link to All Publications

Moore JX, Gilbert KL, Lively KL, Laurent C, Chawla R, Li C, Johnson R, Petcu R, Mehra M, Spooner A, Kolhe R, Ledford CJW. Correlates of COVID-19 Vaccine Hesitancy among a Community Sample of African Americans Living in the Southern United States. Vaccines. 2021; 9(8):879.

Porter G**, Desai K, George V, Coughlin SS, Moore JX*. Racial Disparities in the Epidemiology of COVID-19 in Georgia: Trends Since State-Wide Reopening. Health Equity. 2021;5(1):91-9. Epub 2021/03/30. doi: 10.1089/heq.2020.0089. PubMed PMID: 33778312; PubMed Central PMCID: PMCPMC7990566

Moore JX, Bevel MS, Aslibekyan S, Akinyemiju T. Temporal changes in allostatic load patterns by age, race/ethnicity, and gender among the US adult population; 1988-2018. Prev Med. 2021 Feb 25;:106483. doi: 10.1016/j.ypmed.2021.106483. [Epub ahead of print] PubMed PMID: 33640399

Moore JX, Langston ME, George V, Coughlin SS.  Epidemiology of the 2020 Pandemic of COVID-19 in the State of Georgia: Inadequate Critical Care Resources and Impact after seven weeks of Community Spread.  JACEP Open 2020, in press.

Moore JX, Han Y, Appleton C, Colditz G, Toriola AT. Determinants of Mammographic Breast Density by Race Among a Large Screening Population. JNCI Cancer Spectr. 2020 Apr;4(2):pkaa010. doi: 10.1093/jncics/pkaa010. eCollection 2020 Apr. PubMed PMID: 32373777; PubMed Central PMCID: PMC7192029.

Moore JX, Carter SJ, Williams V, Khan S, Lewis-Thames MW, Gilbert K, Howard G. Physical health composite and risk of cancer mortality in the REasons for Geographic and Racial Differences in Stroke Study. Prev Med. 2020 Mar;132:105989. doi: 10.1016/j.ypmed.2020.105989. Epub 2020 Jan 16. PubMed PMID: 31954141; PubMed Central PMCID: PMC7048236

Moore JX, Royston KJ, Langston ME, Griffin R, Hidalgo B, Wang HE, Colditz G, Akinyemiju T. Mapping hot spots of breast cancer mortality in the United States: place matters for Blacks and Hispanics. Cancer Causes Control. 2018 Aug;29(8):737-750. doi: 10.1007/s10552-018-1051-y. Epub 2018 Jun 19. PubMed PMID: 29922896; PubMed Central PMCID: PMC6301114.

Moore JX, Akinyemiju T, Bartolucci A, Wang HE, Waterbor J, Griffin R. A prospective study of cancer survivors and risk of sepsis within the REGARDS cohort. Cancer Epidemiol. 2018 Aug;55:30-38. doi: 10.1016/j.canep.2018.05.001. Epub 2018 May 25. PubMed PMID: 29763753; PubMed Central PMCID: PMC6054880.

Moore JX, Akinyemiju T, Bartolucci A, Wang HE, Waterbor J, Griffin R. Mediating Effects of Frailty Indicators on the Risk of Sepsis After Cancer. J Intensive Care Med. 2018 Jan 1;:885066618779941. doi: 10.1177/0885066618779941. [Epub ahead of print] PubMed PMID: 29862879; PubMed Central PMCID: PMC6026551.

Xavier Moore J, Donnelly JP, Griffin R, Safford MM, Howard G, Baddley J, Wang HE. Community characteristics and regional variations in sepsis. Int J Epidemiol. 2017 Oct 1;46(5):1607-1617. doi: 10.1093/ije/dyx099. PubMed PMID: 29121335; PubMed Central PMCID: PMC6455035.

Moore JX, Akinyemiju T, Wang HE. Pollution and regional variations of lung cancer mortality in the United States. Cancer Epidemiol. 2017 Aug;49:118-127. doi: 10.1016/j.canep.2017.05.013. Epub 2017 Jun 9. PubMed PMID: 28601785; PubMed Central PMCID: PMC5553699.

Moore JX, Chaudhary N, Akinyemiju T. Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988-2012. Prev Chronic Dis. 2017 Mar 16;14:E24. doi: 10.5888/pcd14.160287. PubMed PMID: 28301314; PubMed Central PMCID: PMC5364735.

Moore JX, Zakai NA, Mahalingam M, Griffin RL, Irvin MR, Safford MM, Baddley JW, Wang HE. Hemostasis biomarkers and risk of sepsis: the REGARDS cohort. J Thromb Haemost. 2016 Nov;14(11):2169-2176. doi: 10.1111/jth.13446. Epub 2016 Sep 23. PubMed PMID: 27512924; PubMed Central PMCID: PMC5503746.

Moore JX, Donnelly JP, Griffin R, Howard G, Safford MM, Wang HE. Defining Sepsis Mortality Clusters in the United States. Crit Care Med. 2016 Jul;44(7):1380-7. doi: 10.1097/CCM.0000000000001665. PubMed PMID: 27105174; PubMed Central PMCID: PMC4911271.