Sex hormones interaction with sex chromosomes in Arterial Stiffening: The goal of this project is to understand the role of sex hormones (estradiol and testosterone) interaction with sex chromosomes complement (XX and XY) in vascular biology. The project utilizes four core genotype mouse model that has a mutated Y chromosome (Y-) and translocated Sry (sex determining) gene to an autosome yielding female mice with (XX or XY-) and male mice with (XXsry or XY-Sry). This project elucidates the role of sex chromosomes, sex hormones, and their interaction in arterial stiffening.
Project: Constitutive deletion of the Xist gene and functional response of vascular smooth muscle cells
Members Activities & News
American Physiological Summit 2024:
Barbara A. Horwitz and John M. Horowitz
Undergraduate Research Award
Anne Kamau, & Ben Ogola
Augusta University white coat ceremony 2024
Graduate School of Biomedical Sciences
Compassion Award
Delphine Okoye, & Ben Ogola
April 4-7 (APS) The American Physiology Summit was held in Long Beach, CA.
Drs. Anil Sakamuri, Anne Kamau, & Ben Ogola
