Vascular Biology - VBIO 9020

Weekly presentation and discussion of recent journal articles that represent an important advance in the field of cardiovascular biology. Students and Postdocs are expected to lead the discussion and answer questions in relation to the paper and field in general.  Specific focus will include "hot" topics and new methodologies related to cardiovascular biology and pathology as they emerge from the literature and how such topics/techniques can be applied to one's own research. The paper discussion will enhance the presentation, problem solving, critical thinking skills of the trainee and his/her ability to provide constructive criticism to improve scientific work.

JC discussions are held in CB-3803 of the Sanders R&E Bldg unless noted otherwise

Journal Club Schedule: Fall 2022 - Spring 2023

 

FALL 2022

Co-Directors:   Dr. Huabo Su  hsu@augusta.edu  | Dr. Gabor Csanyi  gcsanyi@augusta.edu

 

Date Speaker
August 19 Hunter Sellers, PhD Candidate
David Fulton Lab 
Title: "Oocytes maintain ROS-free mitochondrial metabolis by suppressing complex I"
Nature 607:756-761. 2022 / DOI.org/10.1038s41586-022-04979-5
August 26 Brandee Goo, MD/PhD Candidate
Neal Weintraub Lab
Title: "Extracellular Vesicle-based interorgan transport of mitochondria from energetically stressed adiposytes"
Cell Metabolism 33:1853-1868 / DOI.org/10.1016/j.cmet.2021.08.002
September 2 Zsuzsanna Bordan, PhD Candidate
David Fulton Lab
Title: "Chitinase 3-like-1 contributes to the development of pulmonary vascular remodeling in pulmonary hypertension"
JCI Insight.2022 / DOI.org/10.1172/jci.insight.159578 
September 9 Drew Speese, PhD Candidate
David Stepp Lab
Title: "Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity"
Nat Aging 2, 714-725.2022 / DOI.org/10.1038/s43587-022-00261-5
September 16 Steve Haigh, PhD Candidate
David Fulton Lab
Title: "Dichotomous Roles of Smooth Muscle Cell-Derived MCP1 (Monocyte Chemoattractant Protein 1) in Development of Atherosclerosis"
Arterioscler Thromb Vasc Biol. 2022;42:942-956 / DOI.10.1164/ATVBAHA.122.347882
September 23 Jaser Doja, Graduate Student
Joe Miano Lab
Title: "Spatial multi-omic map of human myocardial infarction"
Nature.608,766-777(2022) / DOI.org/10.1038/s41586-022-05060-x
September 30 WonMo Ahn, Graduate Student
Gabor Csanyi Lab
Title: "The Amino Acid homoarginine Inhibits Atherogenesis by Modulating T-Cell Function"
Circulation Research. 2022;131:00-00 / DOI:10.1161/CIRCRESAHA.122.321094
October 7 Candee Barris, Graduate Student
Eric Belin de Chantemele Lab
Title: "Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality"
Science 377:292-297 / DOI:10.1126/science.abn3100
October 14 David Kim, MD/PhD Candidate
Neal Weintraub Lab
Title: "Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms"
J. Exp. Med. 2021. 218(6):1-19.DOI:org/10.1084/jem.20201839
October 21 Ragheb Harb, MD, Postdoctoral Fellow
Neal Weintraub Lab
Title: "Inhibition of macrophage histone demethylas JMJD3 protects against abdominal aortic aneurysms"
J. Exp. Med.2021.218(6):1-19.DOI:org/10.1084/jem.20201839
October 28 Maria Blahove, Graduate Student
Gabor Csanyi Lab
Title: "Extracellular Vesicles From Epicardial Fat Facilitate Atrial Fibrillation"
Circulation. 2021;143:2475–2493.DOI: 10.1161/CIRCULATIONAHA.120.052009
November 4 NO Journal Club
November 11 Zach Brown, Graduate Student
David Fulton Lab
Title: "Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species"
Cell. 2021 Sept 16;184(19):4919-4938.e22 / DOI:10.1016/j.cell.2021.08.028.
November 18 Josue Zambrano-Carrasco, Graduate Student
Huabo Su Lab
Title: "PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle"
Circulation. 2022;145:586–602.DOI:10.1161/CIRCULATIONAHA.121.056666
November 25 NO Journal Club
December 2 Cody Rosewater, Graduate Student
David Stepp Lab
Title: Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library"
Sci. Transl. Med.14(660),eabo0699 / science.org/doi/10.1126/scitranslmed.abo0699
December 9 Mitch Shivers, Graduate Student
David Fulton Lab
Title:  “Robust genome editing in adult vascular endothelium by nanoparticle delivery of  CRISPR-Cas9 plasmid DNA”
Cell Reports 38, Jan 2, 2022 / https://doi.org/10.1016/j.celrep.2021.110196
December 16 Karl Diaz-Sanders, Graduate Student
Jennifer Sullivan Lab
Title: "miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques"
Circ Res. 2021 April 16; 128(8):1122-1138. DOI:10.1161/CIRCRESAHA.120.317914
December 23 and 30 NO Journal Club

 

SPRING 2023

Co-Directors:   Dr. Gabor Csanyi  gcsanyi@augusta.edu  |  Dr. Vijay Ganta vganta@augusta.edu

 

Date Speaker
January 6 Suhib Alhusban, PhD Candidate
Brian Annex Lab
Title: "Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway"
Theranostics 2022,12(11): 5172-5188. doi: 10.7150/thno.71585
January 13 Taylor Kress, PhD Candidate
Eric Belin de Chantemele Lab
Title: "Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis"
Circulation. 2023;147:00–00. DOI: 10.1161/CIRCULATIONAHA.122.061025
January 20 Yoichi Ono, MD, PhD, Postdoctoral Fellow
Eric Belin de Chantemele Lab
Title: "Praliciguat Promotes Ischemic Leg Reperfusion in Leptin Receptor-Deficient Mice"
Circulation Research. 2023;132:34–48. DOI: 10.1161/CIRCRESAHA.122.322033
January 27 Zach Brown, Graduate Student
David Fulton Lab
Title: "Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
Circulation. 2023;147:00–00. DOI: 10.1161/CIRCULATIONAHA.122.058794
February 3 Maria Blahove, Graduate Student
Gabor Csanyi Lab
Title: "Granulocyte microvesicles with a high plasmin generation capacity promote clot lysis and improve outcome in septic shock"
Blood. 2022 Apr 14;139(15):2377-2391 | DOI: 10.1182/blood.2021013328
February 10 Mitch Shivers, Graduate Student
David Fulton Lab
Title: Title Here
publication here
February 17 Cody Rosewater, Graduate Student
David Stepp Lab
Title: "Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis"
Nat Cardiovasc Res. Vol 1:1156–1173 / doi.org/10.1038/s44161-022-00172-z
February 24 Josue Zambrano-Carrasco, Graduate Student
Huabo Su Lab
Title: “Changes in nuclear pore numbers control nuclear import and stress response of mouse hearts”
Developmental Cell 57, 2397–2411 / doi.org/10.1016/j.devcel.2022.09.017
March 3 Adeel Zaidi, PhD, Assistant Research Scientist
Ruth Caldwell Lab
Title: Title Here
publication here
March 10 Amr Salem, PhD, Postdoctoral Fellow
Joe Miano Lab
Title: Title Here
publication here
March 17 No Journal Club  - Graduate Research Day Events (3/16-3/17)
March 24 Shikha Yadav, PhD, Postdoctoral Fellow
Masuko Ushio Lab
Title: Title Here
publication here
March 31 Karl Diaz-Sanders, Graduate Student
Jennifer Sullivan Lab
Title: “CAR T cells produced in vivo to treat cardiac injury”
Science 375, 91–96 (2022) |  DOI: 10.1126/science.abm0594
April 7 No Journal Club - Spring Break
April 14 Anil Sakamuri, PhD, Postdoctoral Fellow
Ben Ogola Lab
Title: Title Here
publication here
April 21 No Journal Club 
April 28 Anita Kovacs-Kasa, PhD, Assistant Research Scientist
Brian Annex Lab
Title: Title Here
publication here
May 5 Sheela Nagarkoti, PhD, Postdoctoral Fellow 
Tohru Fukai Lab
Title: Title Here
publication here
May 12 Yusra Zaidi, PhD, Postdoctoral Fellow
Brian Stansfield Lab
Title: Title Here
publication here
May 19 Tongfeng Cai, Visiting Scholar
Yuqing Hou Lab
Title: Title Here
publication here
May 26 Chen Qui, PhD, Postdoctoral Fellow
Huabo Su Lab
Title: Title Here
publication here