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Biological Sciences
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Creativity, Discovery, Engagement

Learning Like No Other

Programs Get Involved
Students in class
  • Augusta University
  • Science & Mathematics
  • Biological Sciences
  • Research

Research in Biological Sciences

Research in the biological sciences gives students a broader appreciation for their field of study. Research is an excellent way to develop problem-solving and creative thinking skills. In the process, students benefit from increased interactions with fellow students and faculty while they gain confidence through hands-on, real-world experiences in the field and in the lab.

AU Students have the opportunity to present their findings on campus and at regional and national meetings. Meetings include the Georgia Academy of Sciences Conference, the Association of Southeastern Biologists (ASB) Meeting, the Southeastern Estuarine Research Society (SEERS) Meeting, and the Southeastern Regional Yeast Meeting (SERYM), among others. In addition, the Augusta University chapter of Phi Kappa Phi hosts an annual, campus-wide research conference where students present their findings in poster format and oral presentations to the Augusta community.

Throughout the year, the Center for Undergraduate Research and Scholarship hosts the Brown Bag Series where Augusta University students from all disciplines present their research.

Contact Us

Biological Sciences

 Health Sciences Campus

Science & Mathematics Building

706-737-1539

biology@augusta.edu

The Baltzegar Lab

The Baltzegar Lab studies rapid evolution that occurs in response to human-induced changes to the environment in insect vectors with human-health importance, including mosquitoes in the Aedes genus and the German cockroach, Blattella germanica.

Research Interests: Population Genomics / Vector Biology / Ecology / Insecticide Resistance

https://www.augusta.edu/scimath/biological-sciences/baltzegar-research-page.php 

The Goldstein Lab

The Goldstein Lab the pathogenesis and repair of diffuse white matter injury – the most common neuropathological outcome of premature birth.

Research Interests: Brain Injury / Myelin / Epigenetics

https://www.augusta.edu/scimath/biological-sciences/goldstein-research-page.php 

The Langridge Lab

The Langridge Lab focuses on cell-signaling research, particularly on the Notch receptor. Notch is a receptor used in all multicellular animals for cell fate decisions at numerous stages of development and in many aspects of physiology. 

Research Interests: Synthetic Biology / Development / Cell Biology  

https://pauldlangridge.com/ 

Creativity, Discovery, Engagement

Publications

Publication
​

An in vivo screen identifies diverse domains that can act as force-dependent proteolytic switches for Notch activation

Baker, F. C., Harman, J., Jordan, T., Walton, B., Ajamu-Johnson, A., Alashqar, R. F., Bhikot, S., Struhl, G. & Langridge, P. D., Jun 10 2025, In: Science Signaling. 18, 890, eadt4606.

Research output: Contribution to journal › Article › peer-review

​

Sexual dimorphism in the downregulation of extracellular matrix genes contributes to aortic stiffness in female mice

Kamau, A. N., Sakamuri, A., Okoye, D. O., Sengottaian, D., Cannon, J., Guerrero-Millan, J., Sullivan, J. C., Miller, K. S., Liu, Y. & Ogola, B. O., Mar 2025, In: American Journal of Physiology - Heart and Circulatory Physiology. 328, 3, p. H472-H483

Research output: Contribution to journal › Article › peer-review

​

Serine metabolism in aging and age-related diseases

Shan, S. & Hoffman, J. M., Feb 2025, In: GeroScience. 47, 1, p. 611-630 20 p., e2200130.

Research output: Contribution to journal › Review article › peer-review

​

Contact area and tissue growth dynamics shape synthetic juxtacrine signaling patterns

Dawson, J. E., Bryant, A., Walton, B., Bhikot, S., Macon, S., Ajamu-Johnson, A., Jordan, T., Langridge, P. D. & Malmi-Kakkada, A. N., Jan 7 2025, In: Biophysical Journal. 124, 1, p. 93-106 14 p.

Research output: Contribution to journal › Article › peer-review

​

The companion dog as a model for inflammaging: a cross-sectional pilot study

Dog Aging Project Consortium, Dec 2024, In: GeroScience. 46, 6, p. 5395-5407 13 p.

Research output: Contribution to journal › Article › peer-review

​

Cross-sectional survey of 43,517 dogs in the Dog Aging Project identifies owner-reported lifetime prevalence and characteristics of gastrointestinal disease

Dog Aging Project Consortium, Dec 2024, In: Journal of the American Veterinary Medical Association. 262, 12

Research output: Contribution to journal › Article › peer-review

​

Negative effects of lifespan extending intervention on resilience in mice

Corder, K. M., Hoffman, J. M., Sogorovic, A., Yang, Y., Banerjee, A., Sun, Y., Stout, M. B. & Austad, S. N., Nov 2024, In: PloS one. 19, 11 November, e0312440.

Research output: Contribution to journal › Article › peer-review

​

Clippers are superior to scissors in the collection of hair for chemical analysis in companion dogs: a Dog Aging Project preliminary study

Ditzler, B., Evans, J. B., Illing, K., Kaeberlein, M., Promislow, D. E. L., Brindle, E., Hoffman, J. M. & Creevy, K. E., May 2024, In: American Journal of Veterinary Research. 85, 5, p. 1-7 7 p.

Research output: Contribution to journal › Article › peer-review

​

Analysis of 2,570 responses to Dog Aging Project End of Life Survey demonstrates that euthanasia is associated with cause of death but not age

Dog Aging Project Consortium, Feb 2024, In: Journal of the American Veterinary Medical Association. 262, 2, p. 1-10 10 p.

Research output: Contribution to journal › Article › peer-review

​

THE BENEFITS OF A PHYSICAL THERAPY PROGRAM AMONG BREAST CANCER PATIENTS WHO HAVE UNDERGONE A MASTECTOMY

Asbury, E., Bennett, H., Cannon, J. & Kindred, M., 2024, In: Journal of Cancer Rehabilitation. 7, 2, p. 80-92 13 p.

Research output: Contribution to journal › Article › peer-review

​

Amino acid restriction, aging, and longevity: an update

Austad, S. N., Smith, J. R. & Hoffman, J. M., 2024, In: Frontiers in Aging. 5, 1393216.

Research output: Contribution to journal › Review article › peer-review

​

Blockade of interleukin-6 trans-signaling prevents mitochondrial dysfunction and cellular senescence in retinal endothelial cells

Hoffman, J. M., Robinson, R., Greenway, G., Glass, J., Budkin, S. & Sharma, S., Dec 2023, In: Experimental eye research. 237, 109721.

Research output: Contribution to journal › Article › peer-review

​

Production of a p65fl/fl/LysMCre mouse model with dysfunctional NF-κB signaling in bone marrow-derived macrophages

Korkaya, A. K., Fischer, J., Peppers, A., Crosson, S. M., Rayamajhi, M., Miao, E. A., Baldwin, A. S. & Bradford, J. W., Nov 2023, In: Innate Immunity. 29, 8, p. 171-185 15 p.

Research output: Contribution to journal › Article › peer-review

​

Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques

Stout, M. B., Vaughan, K. L., Isola, J. V. V., Mann, S. N., Wellman, B., Hoffman, J. M., Porter, H. L., Freeman, W. M. & Mattison, J. A., Aug 2023, In: GeroScience. 45, 4, p. 2337-2349 13 p.

Research output: Contribution to journal › Article › peer-review

​

Orchiectomy sensitizes cortical bone in male mice to the harmful effects of kynurenine

Bensreti, H., Yu, K., Alhamad, D. W., Shaver, J., Kaiser, H., Zhong, R., Whichard, W. C., Parker, E. G., Grater, L., Faith, H., Johnson, M., Cooley, M. A., Fulzele, S., Hill, W. D., Isales, C. M., Hamrick, M. W. & McGee-Lawrence, M. E., Aug 2023, In: Bone. 173, 116811.

Research output: Contribution to journal › Article › peer-review

​

Lactating SKH-1 furless mice prioritize own comfort over growth of their pups

Hoffman, J. M., Schmitz, B., Pfabe, J. U., Ohrnberger, S. A. & Valencak, T. G., Aug 2023, In: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 193, 4, p. 453-459 7 p.

Research output: Contribution to journal › Article › peer-review

​

Gut Microbiome Transplants and Their Health Impacts across Species

Levine, B. H. & Hoffman, J. M., Jun 2023, In: Microorganisms. 11, 6, 1488.

Research output: Contribution to journal › Review article › peer-review

​

Sulforaphane has an additive anticancer effect to FOLFOX in highly metastatic human colon carcinoma cells

Čižauskaitė, A., Šimčikas, D., Schultze, D., Kallifatidis, G., Bruns, H., Čekauskas, A., Herr, I., Baušys, A., Strupas, K. & Schemmer, P., Nov 2022, In: Oncology Reports. 48, 5, 205.

Research output: Contribution to journal › Article › peer-review

​

Development of a novel purification protocol to isolate and identify brain microglia

Doughty, D., Rajpurohit, S. K., Trang, A., Alptekin, A., Korkaya, A. K., Achyut, B. R., Arbab, A. S. & Bradford, J. W., Aug 2022, In: Experimental Biology and Medicine. 247, 16, p. 1433-1446 14 p.

Research output: Contribution to journal › Article › peer-review

​

MicroRNA cargo of extracellular vesicles released by skeletal muscle fibro-adipogenic progenitor cells is significantly altered with disuse atrophy and IL-1b deficiency

Parker, E., Mendhe, B., Ruan, L., Marshall, B., Zhi, W., Liu, Y., Fulzele, S., Tang, Y. L., McGee-Lawrence, M., Lee, T. J., Sharma, A. K., Johnson, M., Chen, J. & Hamrick, M. W., Aug 2022, In: Physiological Genomics. 54, 8, p. 296-304 9 p.

Research output: Contribution to journal › Article › peer-review

​

The Glucocorticoid Receptor in Osterix-Expressing Cells Regulates Bone Mass, Bone Marrow Adipose Tissue, and Systemic Metabolism in Female Mice During Aging

Pierce, J. L., Sharma, A. K., Roberts, R. L., Yu, K., Irsik, D. L., Choudhary, V., Dorn, J. S., Bensreti, H., Benson, R. D., Kaiser, H., Khayrullin, A., Davis, C., Wehrle, C. J., Johnson, M. H., Bollag, W. B., Hamrick, M. W., Shi, X., Isales, C. M. & McGee-Lawrence, M. E., Feb 2022, In: Journal of Bone and Mineral Research. 37, 2, p. 285-302 18 p.

Research output: Contribution to journal › Article › peer-review

​

Long Non-coding RNA MALAT1 Is Depleted With Age in Skeletal Muscle in vivo and MALAT1 Silencing Increases Expression of TGF-β1 in vitro

Ruan, L., Mendhe, B., Parker, E., Kent, A., Isales, C. M., Hill, W. D., McGee-Lawrence, M., Fulzele, S. & Hamrick, M. W., Jan 21 2022, In: Frontiers in Physiology. 12, 742004.

Research output: Contribution to journal › Article › peer-review

​

Hindlimb Immobilization Increases IL-1β and Cdkn2a Expression in Skeletal Muscle Fibro-Adipogenic Progenitor Cells: A Link Between Senescence and Muscle Disuse Atrophy

Parker, E., Khayrullin, A., Kent, A., Mendhe, B., Youssef El Baradie, K. B., Yu, K., Pihkala, J., Liu, Y., McGee-Lawrence, M., Johnson, M., Chen, J. & Hamrick, M., Jan 3 2022, In: Frontiers in Cell and Developmental Biology. 9, 790437.

Research output: Contribution to journal › Article › peer-review

​

Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model

Yang, L., Wu, C., Parker, E., Li, Y., Dong, Y., Tucker, L., Brann, D. W., Lin, H. W. & Zhang, Q., 2022, In: Theranostics. 12, 5, p. 2205-2231 27 p.

Research output: Contribution to journal › Article › peer-review

​

Absence of MMF1 disrupts heme biosynthesis by targeting Hem1pin Saccharomyces cerevisiae

Whitaker, G. H., Ernst, D. C. & Downs, D. M., Dec 2021, In: Yeast. 38, 12, p. 615-624 10 p.

Research output: Contribution to journal › Article › peer-review

​

Tachycardia evoked from insular stroke in rats is dependent on glutamatergic neurotransmission in the dorsomedial hypothalamus

Marins, F. R., Limborço-Filho, M., Iddings, J. A., Xavier, C. H., Biancardi, V. C., Stern, J. E., Ramiro Diaz, J., Oppenheimer, S. M., Filosa, J. A. & Peliky Fontes, M. A., Nov 2021, In: European Journal of Neurology. 28, 11, p. 3640-3649 10 p.

Research output: Contribution to journal › Article › peer-review

​

Role of fibro-adipogenic progenitor cells in muscle atrophy and musculoskeletal diseases

Parker, E. & Hamrick, M. W., Jun 2021, In: Current Opinion in Pharmacology. 58, p. 1-7 7 p.

Research output: Contribution to journal › Review article › peer-review

​

Decreased parenchymal arteriolar tone uncouples vessel-to-neuronal communication in a mouse model of vascular cognitive impairment

Kim, K. J., Diaz, J. R., Presa, J. L., Muller, P. R., Brands, M. W., Khan, M. B., Hess, D. C., Althammer, F., Stern, J. E. & Filosa, J. A., Jun 2021, In: GeroScience. 43, 3, p. 1405-1422 18 p.

Research output: Contribution to journal › Article › peer-review

​

Mitochondrial DNA Haplotype Diversity in Two Portunid Populations Found along the Georgia and South Carolina Coasts

Abdulovic-Cui, A., Mannix, S., Coleman, A., White, B., Mingledolph, K. & Reichmuth, J. M., May 1 2021, In: Southeastern Naturalist. 20, 2, p. 367-376 10 p.

Research output: Contribution to journal › Article › peer-review

​

Arrb1 regulates metabolic reprogramming to promote glycolysis in stem cell-like bladder cancer cells

Mamouni, K., Kim, J., Lokeshwar, B. L. & Kallifatidis, G., Apr 2 2021, In: Cancers. 13, 8, 1809.

Research output: Contribution to journal › Article › peer-review

​

Targeting mitochondrial metabolism in prostate cancer with triterpenoids

Mamouni, K., Kallifatidis, G. & Lokeshwar, B. L., Mar 1 2021, In: International journal of molecular sciences. 22, 5, p. 1-15 15 p., 2466.

Research output: Contribution to journal › Review article › peer-review

​

Bone Morphogenetic Protein-2 Induces Non-Canonical Inflammatory and Oxidative Pathways in Human Retinal Endothelial Cells

Al-Shabrawey, M., Hussein, K., Wang, F., Wan, M., Elmasry, K., Elsherbiny, N., Saleh, H., Yu, P. B., Tawfik, A. & Ibrahim, A. S., Jan 29 2021, In: Frontiers in immunology. 11, 568795.

Research output: Contribution to journal › Article › peer-review

​

Characterizing the NADPH Oxidase 1-Evoked Pancreatic Stellate Cell Secretome

Chakraborty, A., Souravi, M., Zhi, W., Csanyi, G. & Sabbatini, M., 2021, In: The Arsenal: The Undergraduate Research Journal of Augusta University. 4, 1, p. 6-6 1 p.

Research output: Contribution to journal › Article › peer-review

​

Validation of a Carbohydrate Antigen-19-9 Enzyme-Linked Immunosorbent Assay Kit Using a Mouse Model of Pancreatic Cancer

Mondal, S. & Sabbatini, M., 2021, In: The Arsenal: The Undergraduate Research Journal of Augusta University. 4, 1, p. 27-27 1 p.

Research output: Contribution to journal › Article › peer-review

​

Targeting tumor microenvironment-associated cells to reverse therapy resistance

Piranlioglu, R., Bradford, J. W. & Arbab, A. S., Jan 1 2021, New Targeting in the Reversal of Resistant Glioblastomas. Elsevier, p. 115-144 30 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

​

Cyclic Nucleotides as Mediators of Acinar and Ductal Function

Albers, T. & Sabbatini, M. E., 2021, Cyclic Nucleotides as Mediators of Acinar and Ductal Function. Pancreapedia

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

​

The role of β-arrestins in regulating stem cell phenotypes in normal and tumorigenic cells

Kallifatidis, G., Mamouni, K. & Lokeshwar, B. L., Dec 1 2020, In: International journal of molecular sciences. 21, 23, p. 1-16 16 p., 9310.

Research output: Contribution to journal › Review article › peer-review

​

A novel heme transporter from the energy coupling factor family is vital for group a streptococcus colonization and infections

Chatterjee, N., Cook, L. C. C., Lyles, K. V., Nguyen, H. A. T., Devlin, D. J., Thomas, L. S. & Eichenbaum, Z., Jul 1 2020, In: Journal of Bacteriology. 202, 14, e00205-20.

Research output: Contribution to journal › Article › peer-review

​

Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo

Pierce, J. L., Roberts, R. L., Yu, K., Kendall, R. K., Kaiser, H., Davis, C., Johnson, M. H., Hill, W. D., Isales, C. M., Bollag, W. B., Hamrick, M. W. & McGee-Lawrence, M. E., Feb 2020, In: Experimental Gerontology. 130, 110818.

Research output: Contribution to journal › Article › peer-review

​

Kynurenine signaling through the aryl hydrocarbon receptor: Implications for aging and healthspan

Kaiser, H., Parker, E. & Hamrick, M. W., Feb 2020, In: Experimental Gerontology. 130, 110797.

Research output: Contribution to journal › Review article › peer-review

View All Publications.

View all Publications

Research News

A female scientist, wearing a lab coat and holding a folder of important papers, stands in her lab.

AU research team awarded $4.4 million American Heart Association grant

AU research team awarded $4.4 million American Heart Association grant
A group of ten scientists in lab coats smile at the camera. There are shelves of materials for experiments around them. Two scientists stand in front of the others.

AU scientists’ research on fruit flies published in Biophysical Journal

AU scientists’ research on fruit flies published in Biophysical Journal
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Augusta University researcher helps in the fight against fentanyl

Augusta University researcher helps in the fight against fentanyl

An Education Like No Other

The College of Science and Mathematics provides students with strong foundations in the sciences as well as preparation for careers, citizenship, and a life-long love of learning. We are committed to providing experiences promoting scientific inquiry and discovery and dedicated to creating opportunities for intellectual growth and community involvement.

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