Assistant Professor, Department of Pathology, University of
Alabama, Birmingham, Alabama, 1999-2004
Associate Professor, Institute of Molecular Medicine &
Genetics; Neurology, Georgia Health Sciences University,
2004-2008
Weiss Research Professor, Institute of Molecular Medicine
& Genetics; Neurology, Georgia Health Sciences
University
Research Interests
Cell adhesion and migration are involved in the development
and function of almost every organ. Neurons migrate and extend
axons and dendrites to build the nerve network in the brain.
Osteoclasts attach to the bone matrix to absorb and remodel
bones. Cancer cells migrate to cause tumor metastasis. These
processes require cell adhesion and migration and involve
cytoskeleton reorganization. Cell adhesion to the extracellular
matrix (ECM) activates various signaling pathways and ultimately
leads to actin cytoskeleton reorganization. We are interested in
the molecular mechanisms of how actin cytoskeleton is regulated
by the ECM by using a combination of biochemical ( in vitro),
cell biological (in culture), and genetic mutant animal (in vivo,
including rodents, chicken, and zebrafish animals) studies.
Recognition
National Research Service Award (NIH, USA), 1995-1998
Outside Young Basic Science Faculty Award (MCG), 2007
Grant Awards
NIAMS, NIH (R01), 2002-2012
NINDS, NIH (R01), 2008-2013
Astrazeneca Pharmaceuticals, Inc., 2007-2010
Astrazeneca Pharmaceuticals, Inc., 2007-2008
AHA, Southeastern, GIA, 2007-2009
Training
Postdoctoral Fellow, Department of Microbiology, University
of Virginia Medical College of Georgia, Charlottesville, VA,
199