The mission of BRAG-Onc is to provide a centralized service for biospecimen procurement and distribution across the State of Georgia to advance cancer research. BRAG-Onc was established to represent the diversity of the cancer patient population in Georgia and to enhance cancer research in the state. The repository collects and stores specimens under standardized conditions with accompanying clinical and demographic information. The collection is supported by a web-accessible database for inventory management and annotation, and a long-term storage facility with backups of cryopreserved specimens. The repository serves as the central coordinating center for the statewide network.