Dr. Kumar Vaibhav’s lab is dedicated to explore the mechanism behind immune cells activation post-brain injury.
They have found that immune cells, especially macrophages, T cells and innate lymphoid cells, can be polarized to pro-inflammatory states after injury, which leads to long-term chronic injury and neurological deficits. The lab further reported that modulation of cannabinoid system helps immensely to maintain the equilibrium between different polarized states of immune cells and thus, expediting the recovery from injury. However, PI emphasizes that there is a lot more to explore related to brain injury and role of cannabinoid system in homeostasis.
The lab is funded through several NIH extramural awards and is actively involved in studies related to cannabinoid and non-cannabinoid system in Traumatic brain injury (TBI) and Intracerebral hemorrhages (ICH).
CLICK ON LINKS TO ARTICLES AND PUBLICATIONS ABOUT RESEARCH STUDIES:
CBD may help avert lung destruction in COVID-19CBD may help avert lung destruction in COVID-19
Innate lymphoid cells in TBIInnate lymphoid cells in TBI
Cannabinoids may help limit secondary damage of TBIsCannabinoids may help limit secondary damage of TBIs
TRPV1 in TBI (Receptor that feels the heat of a red chili pepper may be target for TBI recovery)TRPV1 in TBI (Receptor that feels the heat of a red chili pepper may be target for TBI recovery)
Stem cell therapy in strokeStem cell therapy in stroke
Scientists work to dissolve the NETs that worsen TBI damageScientists work to dissolve the NETs that worsen TBI damage
Fine tuning first - responder immune cells may reduce TBI damage
AMPK induces regulatory innate lymphoid cells after traumatic brain injury
WHO (COVID-19, Global literature on coronavirus disease) article
Cannabis and Cannabinoid article