Ruth Caldwell
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Cellular Biology and Anatomy
Medical College of Georgia
Department of Vascular Biology Center
Medical College of Georgia
Department of Culver Vision Discovery Inst
Emeritus Faculty
Bio
I am a founding member of the Vascular Biology Center and the Vision Discovery Institute and VA Career Scientist. I have published over 140 peer reviewed articles and serve on numerous national review panels. My research is supported by grants from the NIH, VA and AHA. Our current focus is on the potential the urea cycle enzyme arginase as therapeutic target for diabetic retinopathy and other forms of ischemic retinopathy.
Education
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Ph.D., Biopsychology.
University of Memphis The, 1979
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MS, Biopsychology
University of Memphis The, 1976
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BA, Mathematics, General
Agnes Scott College, 1964
Awards & Honors
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Keith Green Lectureship
Vision Discovery Institute, 2021
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VA Career Scientist
2015
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Fellow of the AHA
2014
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Excellence in Research Award
2012
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Excellence in Research Award
2009
Courses Taught Most Recent Academic Year
Teaching Interests
Vascular Biology, Retinal Cell Biology
Scholarship
Selected Recent Publications
- ARGINASE: A MULTIFACETED ENZYME IMPORTANT IN HEALTH AND DISEASE, 2018
Manuscript
- Adipose Tissue Constituents and the Adipokine Resistin Impair Vascular Endothelial Function in Obesity via Elevated Arginase Activity, 2017
Conference Proceeding
- Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway (vol 8, e71868, 2013), 2017
Other
- Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis, 2017
Journal Article, Academic Journal
- Netrin-1 is a novel regulator of vascular endothelial function in diabetes, 2017
Journal Article, Academic Journal
Research Interests
The current focus of our group’s research is on the potential of the superoxide generating enzyme NADPH oxidase and the urea cycle enzyme arginase as therapeutic targets for diabetic retinopathy and other forms of ischemic retinopathy.
Department Service
Professional Service
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AHA/Vascular biology review group/reviewer
2013 - Present
Role: Reviewer
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VA IACUC
2010 - Present
Role: Chairperson
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NIH Grant Review
2017 - 2018
Role: Committee Member
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NIH National Eye Institute/Study Section/Ad hoc Review group member
2012 - 2016
Role: Reviewer