Masuko Fukai
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Medicine: Cardiology
The Graduate School
Bio
I have strong expertise on studying role of reactive oxygen species (ROS) (redox) signaling involved in angiogenesis and other cardiovascular and metabolic disease. My lab is the first to demonstrate that ROS derived from NADPH oxidase function as signaling molecule to promote VEGF signaling and angiogenesis as well as post-ischemic neovascularization involved in peripheral arterial disease (PAD).
Courses Taught Most Recent Academic Year
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VBIO 8010
Methods in Cardiovascular Rese
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VBIO 8020
New Frontiers in Vasc Bio
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PHRM 5003
Pharmacology Tutorial
Teaching Interests
Redox signaling in vascular biology and disease
Angiogenesis and peripheral arterial disease
Scholarship
Selected Recent Publications
- Type 1 Diabetes Impairs Endothelium-Dependent Relaxation Via Increasing Endothelial Cell Glycolysis Through Advanced Glycation End Products, PFKFB3, and Nox1-Mediated Mechanisms., 2023
Journal Article, Academic Journal
- Pentose Pathway Activation Is Superior to Increased Glycolysis for Therapeutic Angiogenesis in Peripheral Arterial Disease., 2023
Journal Article, Academic Journal
- Whole-Transcriptome Sequencing Analyses of Nuclear Antixoxidant-1 in Endothelial Cells: Role in Inflammation and Atherosclerosis., 2022
Journal Article, Academic Journal
- Editorial: Mitochondria, metabolism and cardiovascular diseases., 2022
Other
- Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis., 2022
Journal Article, Academic Journal
Research Interests
Vascular Biology, Redox Signaling, Angiogenesis, cardiovascular disease, metabolic disease, endothelial function
Department Service
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VBC Faculty Search Committee
2019 - Present
Role: Committee Member
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VBC post-doc evalulation committee
2018 - Present
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VBC PHD student Oralr Exam committee
2018 - Present
Role: Committee Member
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Review NIH grants for early career invesigators at VBC
2017 - Present
Role: Faculty Advisor
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Director of Redox Signaling Program
2017 - Present
Role: Faculty Advisor
Professional Service
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Reactive Oxygen Species
2018 - Present
Role: Editorial Review Board Member
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NIH
2017 - Present
Role: Reviewer, Grant Proposal
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Editorial Board, Antioxidants
2017 - Present
Role: Editorial Review Board Member
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Editorial Board, Atherosclerosis and Vascular Medicine
2016 - Present
Role: Editorial Review Board Member
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Editorial Board, Journal of Molecular and Cellular Cardiology (JMCC)
2016 - Present
Role: Editorial Review Board Member
