Masuko Fukai
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Medicine: Cardiology
The Graduate School
Bio
I have strong expertise on studying role of reactive oxygen species (ROS) (redox) signaling involved in angiogenesis and other cardiovascular and metabolic disease. My lab is the first to demonstrate that ROS derived from NADPH oxidase function as signaling molecule to promote VEGF signaling and angiogenesis as well as post-ischemic neovascularization involved in peripheral arterial disease (PAD).
Courses Taught Most Recent Academic Year
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VBIO 9300
Research in Vascular Bio
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VBIO 9010
Seminar in Vascular Bio
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BIOM 8040
Intro to Faculty Research
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VBIO 8010
Methods in Cardiovascular Rese
Teaching Interests
Redox signaling in vascular biology and disease
Angiogenesis and peripheral arterial disease
Scholarship
Selected Recent Publications
- Modification of Cardiac Progenitor Cell-Derived Exosomes by miR-322 Provides Protection against Myocardial Infarction through Nox2-Dependent Angiogenesis., 2019
Journal Article, Academic Journal
- Oxidant Signaling Mediated by Nox2 in Neutrophils Promotes Regenerative Myelopoiesis and Tissue Recovery following Ischemic Damage., 2018
Journal Article, Academic Journal
- Copper transporter ATP7A interacts with IQGAP1, a Rac1 binding scaffolding protein: role in PDGF-induced VSMC migration and vascular remodeling., 2018
Journal Article, Academic Journal
- Copper Transporters and Copper Chaperones: Roles in Cardiovascular Physiology and Disease., 2018
Journal Article, Academic Journal
- Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence., 2018
Journal Article, Academic Journal
Research Interests
Vascular Biology, Redox Signaling, Angiogenesis, cardiovascular disease, metabolic disease, endothelial function
Department Service
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VBC Faculty Search Committee
2019 - Present
Role: Committee Member
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VBC post-doc evalulation committee
2018 - Present
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VBC PHD student Oralr Exam committee
2018 - Present
Role: Committee Member
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Review NIH grants for early career invesigators at VBC
2017 - Present
Role: Faculty Advisor
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Director of Redox Signaling Program
2017 - Present
Role: Faculty Advisor
Professional Service
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Reactive Oxygen Species
2018 - Present
Role: Editorial Review Board Member
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NIH
2017 - Present
Role: Reviewer, Grant Proposal
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Editorial Board, Antioxidants
2017 - Present
Role: Editorial Review Board Member
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Editorial Board, Atherosclerosis and Vascular Medicine
2016 - Present
Role: Editorial Review Board Member
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Editorial Board, Journal of Molecular and Cellular Cardiology (JMCC)
2016 - Present
Role: Editorial Review Board Member