Darren Browning
                                                                                Professor
                                        Academic Appointment(s)
Medical College of Georgia
Department of Biochemistry and Molecular Biology
Administration
Department of The Graduate School
                                                                                 Bio
Educated at University of Toronto in cellular and developmental biology, post-doc in immunology at The Scripps Research Institute (La Jolla, CA). Research Faculty in University of Illinois at Chicago.
                                     
                                 
                                
                                
                                
                                
                             
                            
                            
                            
                            
                            
                            
                                                                    Education
                                    
                                        - 
Ph.D., Cell/Cellular Biology and Histology
University of Toronto, 1995
 
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MS, Biology/Biological Sciences, General
University of Toronto, 1990
 
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BS, Cell/Cellular Biology and Histology
University of Toronto, 1988
 
                                        
                                    
                                                                        Awards & Honors
                                    
                                        - 
Best of Cancer Prevention Research
American Association for Cancer Research, 2019
 
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Distinguished Teacher Award
The Graduate School, 2017
 
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Outstanding Service Award
The Graduate School, 2017
 
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Caught in the act of Leadership and Collegiality
AU office of Faculty Development and Teaching Excellence, 2014
 
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Distinguished Service Award
The Graduate School, Augusta University, 2011
 
                                        
                                    
                                    
                             
                            
                            
                                
                                    
                                                                             Courses Taught Most Recent Academic Year
                                        
                                        
                                            - 
BIOM 8021
Biochem & Gene Regulation
 
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MEDI 6120
Foundations of Medicine
 
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BIOM 8022
Molecular Cell Biology
 
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MEDI 6130
Musculoskeletal/Skin
 
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MEDI 6220
Cardiopulmonary/Heme
 
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BCMB 8201
Cur Topics & Tech in MB
 
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MEDI 6240
GI/GU/Endocrine
 
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MEDI 5005
Integrative Science
 
                                        
                                                                                 Teaching Interests 
                                        Large-group lectures: Signal transduction, carbohydrate structure and metabolism (glycolysis, gluconeogenesis, glycogen metabolism).  Smaller group discussion: molecular cloning, protein purification, cyclic-nucleotide signaling, scientific communication.
                                        
                                    
                                 
                             
                            
                            
                            
                                                                     Scholarship 
                                    Selected Recent Publications
                                                                    
                                    - Upregulation of the EGFR/MEK1/MAPK1/2 signaling axis as a mechanism of  resistance to antiestrogen‑induced BimEL dependent apoptosis in ER(+) breast  cancer cells., 2023
 Journal Article, Professional Journal
 
- Type-2 cGMP-dependent protein kinase suppresses proliferation and carcinogenesis in the colon epithelium, 2022
 Journal Article, Professional Journal
 
- Inhibition of colon cancer cell growth by phosphodiesterase inhibitors is independent of cGMP signaling, 2022
 Journal Article, Professional Journal
 
- The Campylobacter jejuni Response Regulator and Cyclic-Di-GMP Binding CbrR Is a  Novel Regulator of Flagellar Motility., 2021
 Journal Article, Academic Journal
 
- Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation, 2019
 Journal Article, Academic Journal
 
                                
                                                                    Research Interests
                                    Gastrointestinal disorders, colorectal cancer, inflammatory bowel disease, irritable bowel disease, inflammation, epithelial biology. Signaling by cGMP, guanylyl cyclases, cGMP-dependent protein kinases.
                                                                 
                            
                            
                            
                                
                                                                                                                 College Service
                                        
                                            - 
Three Minute Thesis Competition
2016 - Present
Role:  Committee Chair
 
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Graduate Faculty Appointment subcommittee of the Graduate Council
2016 - Present
Role:  Committee Member
 
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Graduate Council
2014 - Present
Role:  Committee Member
 
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MD-PhD Admissions Committee
2013 - Present
Role:  Committee Member
 
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Recruitment and Acceptance Committee
2006 - Present
Role:  Committee Member
 
                                            
                                        
                                                                                                                                                         Professional Service
                                        
                                            - 
United States Department of Veterans Affairs
2019 - 2019
Role:  Reviewer, Ad Hoc Reviewer
 
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United States Department of Veterans Affairs
2019 - 2019
Role:  Reviewer, Ad Hoc Reviewer
 
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AACR/Undergraduate Student Poster Competition/Judge
2019 - 2019
Role:  Reviewer
 
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United States Department of Veterans Affairs
2018 - 2018
Role:  Reviewer, Ad Hoc Reviewer
 
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United States Department of Veterans Affairs
2018 - 2018
Role:  Committee Chair
 
                                            
                                        
                                                                                                                     Public Service