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Center for Excellence in Research, Scholarship, and Innovation (CERSI)

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Driving the Future of Oral Health

At The Dental College of Georgia, research is a mission to transform global health and elevate patient care. In collaboration with other units of Augusta University and the University System of Georgia, our multidisciplinary teams lead groundbreaking research in the diagnosis, prevention, and treatment of complex oral and dental diseases. By uniting world-class faculty across basic, translational, and clinical science, we rapidly bridge the gap between laboratory discovery and life-changing clinical practice.

Fostering Collaborative Excellence

Through strategic institutional collaboration, CERSI serves as a catalyst for innovation and academic growth. We actively recruit top-tier research talent, secure competitive funding, and build integrated research programs designed to address the most pressing challenges in orofacial health. Our collaborative ecosystem provides the infrastructure, mentorship, and support necessary to turn bold scientific ideas into measurable health outcomes.

Publication
​

Effects of mitochondrial complex I subunit NDUFS5 deficiency on osteogenic differentiation

Peng, J., Zhang, Q., Zhang, X., Wei, Z., Parviainen, A., Killedar, D., Tay, F. & Chen, M., Dec 2026, In: Journal of Dentistry. 175, 106935.

Research output: Contribution to journal › Article › peer-review

​

Bidirectional integrin β1 activation synergizes neurovascular coupling and enhances bone regeneration

Wu, F., An, Y., Zhao, Y., Yu, J., Wu, G., Tay, F. R., Jiao, Y. & Wang, J., Dec 2026, In: Nature communications. 17, 1, 7610.

Research output: Contribution to journal › Article › peer-review

​

Cristae: bridging bioenergetic hubs and compartmental barriers in mitochondrial homeostasis

Rao, J., Wan, Q. Q., Chen, L., Tang, R. B., Killedar, D., Tay, F. & Niu, L. N., Dec 2026, In: Cell Death and Disease. 17, 1, 552.

Research output: Contribution to journal › Review article › peer-review

​

Correction: Regulation of immune microenvironments by polyetheretherketone surface topography for improving osseointegration (Journal of Nanobiotechnology, (2025), 23, 1, (199), 10.1186/s12951-025-03272-7)

Zhao, Y., An, Y., Wu, F., Liu, L., Tay, F. R., Jiao, Y. & Wang, J., Dec 2026, In: Journal of Nanobiotechnology. 24, 1, 336.

Research output: Contribution to journal › Comment/debate › peer-review

​

Bone adhesive with temporally-synchronized degradation for enhanced osteointegration

Gu, J. T., Li, Z. T., Wang, Y. Z., Hao, D. X., Dang, G. P., Cao, X. Q., Tay, F. R., Chen, J. H., Aparicio, C., Jiao, K. & Niu, L. N., Dec 2026, In: Bone Research. 14, 1, 39.

Research output: Contribution to journal › Article › peer-review

​

Comparative analysis of heat impacts on bond strength and failure modes of calcium silicate- and epoxy resin-based sealers

Kandil, N. M., Elashiry, M. M., Wong, B. & Elgendy, A. A., Dec 2026, In: BMC Oral Health. 26, 1, 893.

Research output: Contribution to journal › Article › peer-review

​

Fibulin-1 is required for microvascular integrity in the developing brain and retina

Chen, X., Singhania, H., Zaidi, S. A. H., Tandon, I., Grant, R. I., Caldwell, R. B. & Cooley, M. A., Nov 2026, In: Developmental Biology. 539, p. 5-17 13 p.

Research output: Contribution to journal › Article › peer-review

​

Perforating external root resorption with periodontal-derived osseous ingrowth: a radiographic mimic of internal replacement resorption

Ricucci, D., Tsukiboshi, M., Milovidova, I., Qu, Y., Gu, L. & Tay, F., Oct 2026, In: Journal of Dentistry. 173, 106747.

Research output: Contribution to journal › Article › peer-review

​

Systemic recalibration and epigenetic resetting as complementary strategies in ageing biology

Li, Y. Y. & Tay, F. R., Oct 2026, In: Ageing Research Reviews. 121, 103227.

Research output: Contribution to journal › Review article › peer-review

​

Robot-assisted haptic guidance in endodontics: A pilot study evaluating efficiency and tooth structure preservation

Momen, R., Dale, J., Suresh, M., Ravenel, T. D., Marshall, J. & Hahn, C. L., Oct 2026, In: Journal of Dentistry. 173, 106854.

Research output: Contribution to journal › Article › peer-review

​

Nasopalatine duct cysts, case series of 106 cases with radiographic presentation and review of the literature

Buchanan, A., Charmelo, S., Namazi, F., Richards, M., Kalathingal, S., Kurago, Z. & Abdelsayed, R., Oct 2026, In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 142, 4, p. 648-663 16 p.

Research output: Contribution to journal › Article › peer-review

​

Cuproptosis in Endodontics: Potential Mechanisms and Therapeutic Applications

Li, Y. Y. & Tay, F., Sep 2026, In: Journal of endodontics. 52, 9, p. 1393-1403 11 p.

Research output: Contribution to journal › Review article › peer-review

​

Resensitizing drug-resistant cancers by co-targeting apoptosis and mitochondrial stress pathway

Sethi, G., Rahimmanesh, I., Davoodi, A., Chen, Y., Tay, F. R., Bhol, C. S., Makvandi, P. & Xu, Y., Sep 2026, In: Drug Resistance Updates. 88, 101443.

Research output: Contribution to journal › Review article › peer-review

​

Evaluation of dentinal microcrack formation during endodontic microsurgery: a micro-CT evaluation of piezoelectric root resection and root-end preparations with ultrasonic tips

Lynn, M., Ravenel, T., Emecen-Huja, P. & Eppes, K., Sep 2026, In: Journal of Dentistry. 172, 106780.

Research output: Contribution to journal › Article › peer-review

​

Insights into the August 2026 Issue of the JOE

Aminoshariae, A., Azarpazhooh, A., Glickman, G. N., He, J., Kim, S. G., Kishen, A., Letra, A. M., Levin, L., Ordinola-Zapata, R., Setzer, F. C., Tay, F. R. & Hargreaves, K. M., Aug 2026, In: Journal of endodontics. 52, 8, p. 1233-1235 3 p.

Research output: Contribution to journal › Editorial › peer-review

​

Cepharanthine improves blood glucose levels and mitigates renal injury in streptozotocin-induced diabetic rats via restoring pancreatic β-cell integrity and reducing inflammation

Katary, M. A., Samra, Y. A., Saad, K. M., Capehart, K., Abdelsayed, R. & Elmarakby, A. A., Jul 2026, In: Frontiers in Pharmacology. 17, 1807706.

Research output: Contribution to journal › Article › peer-review

​

Correction: Bioactive Carboxymethyl Starch-Based Hydrogels Decorated with CuO Nanoparticles: Antioxidant and Antimicrobial Properties and Accelerated Wound Healing In Vivo (International Journal of Molecular Sciences, (2021), 22, 5, (2531), 10.3390/ijms22052531)

Abdollahi, Z., Zare, E. N., Salimi, F., Goudarzi, I., Tay, F. R. & Makvandi, P., Jul 2026, In: International journal of molecular sciences. 27, 13, 5896.

Research output: Contribution to journal › Comment/debate › peer-review

​

Insights into the July 2026 Issue of the JOE

Aminoshariae, A., Azarpazhooh, A., Glickman, G. N., He, J., Kim, S. G., Kishen, A., Letra, A. M., Levin, L., Ordinola-Zapata, R., Setzer, F. C., Tay, F. R. & Hargreaves, K. M., Jul 2026, In: Journal of endodontics. 52, 7, p. 1079-1081 3 p.

Research output: Contribution to journal › Editorial › peer-review

​

The effect of hydrodynamic shear on sodium hypochlorite disinfection of Enterococcus faecalis biofilms in dentinal tubules

Li, Q., Liu, H., Hieawy, A., Wang, X., Xiao, L., Tay, F. R. & Shen, Y., Jul 2026, In: Journal of Dentistry. 170, 106694.

Research output: Contribution to journal › Article › peer-review

​

Sex differences in the renal T cell profile in DOCA-salt hypertension are independent of MR activation and increases in blood pressure

Mohamed, R., Belanger, K. M., Moronge, D., Elmarakby, A. A. & Sullivan, J. C., Jul 2026, In: American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 331, 1, p. F82-F92

Research output: Contribution to journal › Article › peer-review

​

Allergenic and cytotoxic potential of (meth)acrylate monomers in dental materials: a narrative review

Smidtas, L., Johnson, J., Pacheco, R. R. & Jauregui, C., Jun 24 2026, In: Frontiers in Dental Medicine. 7, 1846292.

Research output: Contribution to journal › Review article › peer-review

​

Insights into the June 2026 Issue of the JOE

Aminoshariae, A., Azarpazhooh, A., Glickman, G. N., He, J., Kim, S. G., Kishen, A., Letra, A. M., Levin, L., Ordinola-Zapata, R., Setzer, F. C., Tay, F. R. & Hargreaves, K. M., Jun 2026, In: Journal of endodontics. 52, 6, p. 847-849 3 p.

Research output: Contribution to journal › Editorial › peer-review

​

Effect of Lactate Metabolism on Hypoxia-induced Inflammation in the Oral Mucosa

Zhu, Y., Xu, K., Wei, Y., Gu, J., Cao, X., Yu, L., Zhang, Z., Wu, S., Chen, J., Jiao, K., Tay, F., Gao, P., Wan, M. & Niu, L., Jun 2026, In: Journal of Dentistry. 169, 106664.

Research output: Contribution to journal › Article › peer-review

​

Evaluation of dentinal microcrack formation during endodontic microsurgery: a micro-CT evaluation of piezoelectric root resection and root-end preparations with ultrasonic tips

Lynn, M. & Ravenel, T. D., May 19 2026, In: Journal of Dentistry.

Research output: Contribution to journal › Article › peer-review

​

Mitochondria serve as a source of mineral precursors initiating early cartilage calcification in osteoarthritis

Wan, Q., Ye, T., Gu, J., Ma, Y., Qin, W., Yan, J., Rao, J., Chen, L., Hao, D., Tay, F. R., Jiao, K. & Niu, L., May 15 2026, In: Science Bulletin. 71, 9, p. 2300-2315 16 p.

Research output: Contribution to journal › Article › peer-review

​

Insights Into the May 2026 Issue of the JOE

Aminoshariae, A., Azarpazhooh, A., Glickman, G. N., He, J., Kim, S. G., Kishen, A., Letra, A. M., Levin, L., Ordinola-Zapata, R., Setzer, F. C., Tay, F. R. & Hargreaves, K. M., May 2026, In: Journal of endodontics. 52, 5, p. 685-687 3 p.

Research output: Contribution to journal › Editorial › peer-review

​

Protective Role of CBD Against Nicotine Pouch–Induced Seizure Aggravation and Alterations in Brain Glymphatic Biomarkers

Bhandari, B., Naeini, S. E., Rogers, H. M., Alhashim, A. H., Yu, J. C., Seyyedi, M., Young, N., El-marakby, A., Salles, É. L., Wang, L. P. & Baban, B., May 2026, In: Nicotine and Tobacco Research. 28, 5, p. 848-856 9 p.

Research output: Contribution to journal › Article › peer-review

​

Tryptophan metabolites 3-hydroxykynurenine (3HK) and 3-hydroxyanthranilic acid (3HAA) increase oxidative stress and impair osteoblastic bone formation

Alhamad, D. W., Bensreti, H., Ding, K., Sultana, S., Yearwood, C. L., Ellingwood, A., Shaver, J., Burkhart, K., Tripathi, A., Dorn, J., Cushing, M., Nesbit, H., Dai, C., Morey, E., Gross, C., Alhamad, M., Taylor, D., Cherezova, A., Ilatovskaya, D. V. & Zhi, W. & 9 others, Cooley, M. A., Zhong, R., Johnson, M. H., Bollag, W. B., Hamrick, M. W., Fulzele, S., Hill, W. D., Isales, C. M. & McGee-Lawrence, M. E., Apr 2026, In: Journal of Biological Chemistry. 302, 4, 111174.

Research output: Contribution to journal › Article › peer-review

​

Insights into the April 2026 Issue of the JOE

Aminoshariae, A., Azarpazhooh, A., Glickman, G. N., He, J., Kim, S. G., Kishen, A., Letra, A. M., Levin, L., Ordinola-Zapata, R., Setzer, F. C., Tay, F. R. & Hargreaves, K. M., Apr 2026, In: Journal of endodontics. 52, 4, p. 509-511 3 p.

Research output: Contribution to journal › Editorial › peer-review

​

Pachyonychia Congenita: Clinical and Pathological Case Report

Cornelius Timothius, C. J., Stern, I., Stern, J. K., Abdelsayed, R. A., Ghaly, M. & Peacock, M. E., Feb 2026, In: Journal of Dentistry and Oral Epidemiology.

Research output: Contribution to journal › Article › peer-review

​

The role of artificial intelligence in shaping dentistry through advancement in data acquisition, clinical practice, education, and research

Tay, F. C. M., Loveless, R. & Ravenel, T. D., Jan 14 2026, In: Dental Research Journal.

Research output: Contribution to journal › Article › peer-review

​

PEEK surface treatments for resin bonding: A systematic review and network meta-analysis of in vitro studies

Vitti, R. P., de Oliveira, S. G., Pecorari, V. G. A., Brandt, W. C., Nunes Leite Lima, D. A., Pacheco, R. R. & Aguiar, F. H. B., 2026, (Accepted/In press) In: Dental Materials.

Research output: Contribution to journal › Review article › peer-review

​

Chemical-Biological Fixation for Enhanced Bone Augmentation in Guided Bone Regeneration

Wang, Y. Z., Dang, G. P., Li, Z. T., Feng, Z. H., Bai, Q., Hao, J. X., Cao, X. Q., Ye, T., Li, J., Tay, F. R., Xing, M., Fang, M., Gu, J. T. & Niu, L. N., 2026, (Accepted/In press) In: Advanced Science.

Research output: Contribution to journal › Article › peer-review

​

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

Dang, G. P., Wang, Y. Z., Wang, Y. F., Bai, Q., Hao, J. X., Li, Z. T., Cao, X. Q., Wei, Y., Feng, Y., Chen, J. H., Tay, F. R., Wang, R. B., Gu, J. T. & Niu, L. N., 2026, (Accepted/In press) In: BMEMat.

Research output: Contribution to journal › Review article › peer-review

​

Endodontic Management Before, During and After Head and Neck Radiotherapy: Biological, Diagnostic and Clinical Considerations in Head and Neck Cancer Patients

Ma, J. Z. & Tay, F., 2026, (Accepted/In press) In: International Endodontic Journal.

Research output: Contribution to journal › Review article › peer-review

​

The use of ozone in oral health care: a narrative review of current evidence and clinical applications

Jauregui, C., Chike, G., Khoshneviszadeh, S. & Killedar, D., 2026, In: Frontiers in Oral Health. 7, 1846309.

Research output: Contribution to journal › Review article › peer-review

​

Association between resting-state alpha oscillations and postoperative pain following endodontic treatment

Hammad, A. R., Elashiry, M. M., Mansour, A. H., Elbokl, A., Nagy, M. M., Sinibaldi, J., Bergeron, B. E., Haddadeen, H. & Hashem, A. A., 2026, (Accepted/In press) In: Odontology.

Research output: Contribution to journal › Article › peer-review

​

Transformative comprehensive functional and esthetic rehabilitation of amelogenesis imperfecta: An interdisciplinary approach

Londono, J., Rattansi, S., Patel, P., Fortson, W. M., Torosian, A. & Silas, J., 2026, (Accepted/In press) In: Journal of Prosthetic Dentistry.

Research output: Contribution to journal › Article › peer-review

​

Harnessing Cannabis sativa as a dual-use platform for biohydrogen production and pharmaceutical synthesis: a hypothesis and theory

Wang, L. P. & Baban, B., 2026, In: Frontiers in Plant Science. 17, 1833491.

Research output: Contribution to journal › Article › peer-review

​

Microstructural evolution of cold-worked titanium dental implants following clinically relevant insertion torque

Elkahly, M., Elshewy, M., Pacheco, R., Messer, R. & Thompson, G. A., 2026, (Accepted/In press) In: Journal of Prosthodontics.

Research output: Contribution to journal › Article › peer-review

View All Publications.

Empowering the Next Generation of Scholars

Pre-doctoral students and post-doctoral residents enrolled in Advanced Education programs at the Dental College of Georgia are encouraged to gain research experience with faculty mentors and present their findings at local, state, national, and international meetings. Students may be candidates for the M.S. or PhD degree through the graduate program of the Department of Oral Biology.  The center also offers a seminar series focused on research topics related to the various areas of research.

CERSI News

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SGA Dental Partners plans $2.5M gift to Dental College of Georgia Savannah

SGA Dental Partners plans $2.5M gift to Dental College of Georgia Savannah
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Nursing professor partners with DCG for screenings of high-risk patients

Nursing professor partners with DCG for screenings of high-risk patients
Student explains her research to onlookers

DCG dental research symposium welcomes hundreds

DCG dental research symposium welcomes hundreds

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