Transgenic and Genome Editing Core Facility

Lin Gan, PhD

Director,  Genome Editing Core

ABOUT THE CORE

The Genome Editing Core is a full-service facility supported by Augusta University, The Georgia Research Alliance, and user fees. The Core’s mission is to provide timely and cost-effective services in all phases of transgenic mouse production by pronuclear microinjection into zygotes, gene targeting in embryonic stem cells (ESCs), and gene editing using CRISPR/Cas9 approach to the research community at Augusta University as well as other academic institutions and for-profit companies. The Core also provides services on preserving your valuable lines by cryopreservation of sperms and embryos, and resurrecting mouse lines using in vitro fertilization (IVF) or embryo transfer. Additional services include rederivation to create pathogen-free mouse lines, developing molecular reagents for genetic engineering, full colony management services, and expert advice on mouse genetics and breeding schemes.

Consultation	Services	Project Request
Consultations are provided at no cost. We provide advice, as well as, protocols for every step of the process, from experimental design, to mouse breeding.  Please contact us at any time with questions on how to proceed.	CRISPR/Cas9 Gene Editing	Augusta University faculty and staff should review our service rate and submit service request by iLab. REQUEST PROJECT

LOCATION:
The Core consists of a wet lab for molecular biology, cell culture, and embryo microinjection in Room CA3056 of Department of Neurosciences and Regenerative Medicine, and an animal housing and procedure rooms in Suite CA1117. The Core is fully equipped to carry out the all procedures of generating mouse models as well as related services.

HOURS OF OPERATION:
Monday through Friday 8:00AM – 5:00PM. The core will follow the Augusta University calendar for holidays.

ACKNOWLEDGEMENT:
All work performed by Augusta University Genome Editing Core should be acknowledged in scholarly publications, posters, and oral presentations. Proper recognition allows us to measure the impact of our work and supports our initiatives in obtaining sponsored funding. When you use this resource, please be sure to include the following acknowledgement: 

We gratefully acknowledge the Genome Editing Core at Augusta University for generating the mouse models necessary to support this research.