
Since the establishment of the department, laboratory and clinical research have been
and continue to be important endeavors.
Just as the best clinical care evolves in a situation designed for the best learning
experience, an inquisitive critical atmosphere naturally leads to clinical and laboratory
research by the participants. Thus all of our full-time faculty have been involved
in research to a varying degree, and all residents are encouraged to participate in
some type of research. Because research in the clinical sciences is nurtured by advances
in the basic sciences, interdisciplinary relationships have been developed and continue
to contribute to the research programs in the department.
Major Laboratory Investigations
- The biochemistry of keratinization
- Keratinous acid glycosaminoglycans
- Aging and disease changes in skin connective tissue
- Cutaneous blistering and lysosomes
- Elastic tissue diseases
- Effects of burns on skin metabolism
- Epidermal ribonucleases and nucleotides
- Biochemical changes in psoriatic scale
- Effects of methotrexate and ethanol drug interactions and effects on the liver
- The epidermal cell cycle in normal, psoriatic, and malignant skin
- Corticosteroid - induced cutaneous atrophy
- Role of immunocytes and immunosuppressants in aging
- Effects of vitamin A and corticosteroids on granulomas
Clinical Research
Historical and Completed Clinical Investigations
- Evaluation of potent topical steroids in terms of systemic absorption and efficacy
- New therapeutic agents for acne vulgaris
- New therapeutic agents for superficial fungal infections
- Hair root protein analysis as a measure of human protein malnutrition
- Skin reactive factors in Candida Albicans
- Therapeutic agents in congenital porphyria
- New topical corticosteroids for the treatment of psoriasis
- Phenytoin treatment of epidermolysis bullosa
- Hepatitis B infections in dermatology
- Nutritional factors such as selenium in prevention of skin cancer
- Effects of Lac-Hydrin on Keratosis Pilaris
- Assessment of photodamaged skin treated with topical isotretinoin
- Treatment of patients with onychomycosis of the toenails with Terbinafine
- Treatment of basal cell carcinoma with fluorouracil / epinephrine injectable gel
- Use of topical imiquimod cream to treat visible, external genital / perianal warts
in male and female patients
- Use of oral Valtrex 500 mg to treat recurrent genital herpes
- Use of topically applied tacrolimus to treat atopic dermatitis in pediatric patients
- Use of butenafine to treat Tinea Pedis
- Use of topically applied tacrolimus to treat atopic dermatitis in adult patients
- Prevention of cheilitis associated with oral isotretinoin treatment in severe nodular
acne patients