Core Faculty

Eric J. Belin de Chantemèle, D.Sc

Eric J. BELIN de Chantemèle, D.Sc

Associate Professor

Department of Medicine, Cardiology
 


Contact Info

Phone: (706) 721-7805
Fax: (706) 721-9799
Email: ebelindechanteme@augusta.edu
Office: CB 3212B
Lab: CB-3205

Education and Training

Postdoctoral Training
Medical College of Georgia,
Augusta, GA.
Vascular Biology Center
2006-2010

Postdoctoral Training
Faculté de Médecine,
Angers, FRANCE.
Laboratory of Integrated Neurovascular Biology.
UMR-CNRS 6214 INSERM U77
2005-2006

D.Sc.
Université Claude Bernard
Lyon I,
Faculté de Médecine Lyon Grange Blanche.
Laboratoire de Physiologie de l’Environnement

Department of Autonomic Neuroscience.
Research Institute of Environment Medicine.
Nagoya University, JAPAN
2005

M.S
Université Claude Bernard
Lyon I,
Faculté de Médecine Lyon Grange Blanche.
Laboratoire de Physiologie de l’Environnement.
2002

B.Sc.
Université Claude Bernard
Lyon I,
2000

Society Memberships

  • American Heart
    Association
  • American Physiological Society


Research

The main goal of the laboratory is to analyze the mechanisms whereby metabolic disorders such as obesity, diabetes and lipodystrophy, lead to cardiovascular disease. More specifically, we are interested in determining the contribution of leptin, a hormone secreted by the adipose tissue, to vascular disease and hypertension. A major focus of the lab is to understand the sex-specificity of the mechanisms leading to cardiovascular disease in obesity and diabetes and to understand how metabolic disorders abrogate the protective effects of female sex hormones.  All experiments are conducted in close collaboration with physicians and involve an integrative approach consisting of a wide range of physiological, pharmacological and molecular methods, and involving genetically engineered mouse models of disease.

Lab

Galina Antonova

Galina Antonova
Research Assistant  

Simone Kennard

Simone Kennard
Research Associate

Thiago Bruder do Nascimento

Thiago Bruder do Nascimento
Postdoctoral Fellow

Jessica Faulkner

Jessica Faulkner
Postdoctoral Fellow


Honors and Awards

2016 - Augusta University Research Institute Virenda B. Mahesh Distinguished Research Award.

2016 - Medical College of Georgia Faculty Senate Award for Young Outstanding Basic Science Faculty.

2015 - Dean Franklin Young Investigator Award, American Physiological Society.

2012 - New Investigator Award, Cardiovascular Section, American Physiology Society.

Publications

Go to PUBMED for more publications

Huby, G. Antonova, J. Groenendyk, CE. Gomez-Sanchez, WB. Bollag, JA. Filosa, EJ. Belin de Chantemèle. The Adipocyte-Derived Hormone Leptin is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis. (2015) Circulation. 132(22):2134-45.
Paper recommended by Faculty of 1000

Huby, L. Otvos, EJ. Belin de Chantemèle. Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice. (2016). Hypertension. 67(5):1020-8

Bruder-Nascimento, KK. Bence, and EJ. Belin de Chantemèle. POMC Ptp1b Deletion increases energy expenditure and impairs endothelial function via TNF-α dependent mechanisms. (2016) Clin Sci. 130(11):881-93.

Bruder-Nascimento, BR. Butler, DJ. Herren, MW. Brands, KK. Bence, EJ. Belin de Chantemèle. Deletion of protein tyrosine phosphatase 1b in proopiomelanocortin neurons reduces neurogenic control of blood pressure and protects mice from leptin- and sympatho-mediated hypertension. (2015) Pharmacol Res. 102:235-44.

Herren, JB. Norman, R. Anderson, ML. Tremblay, AC. Huby and EJ. Belin de Chantemèle. Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial Dysfunction. (2015), PLOS ONE. 10(5):e0126866.