Eric Belin de Chantemele, DSc
- The main goal of Belin de Chantemele’s laboratory is to analyze the mechanisms whereby
metabolic disorders such as obesity, diabetes and lipodystrophy, lead to cardiovascular
disease. More specifically, they are interested in determining the contribution of
leptin, a hormone secreted by the adipose tissue, to vascular disease and hypertension.
A major focus of the lab is to understand the sex-specificity of the mechanisms leading
to cardiovascular disease in obesity and diabetes and to understand how metabolic
disorders abrogate the protective effects of female sex hormones. All experiments
are conducted in close collaboration with physicians and involve an integrative approach
consisting of a wide range of physiological, pharmacological and molecular methods,
and involving genetically engineered mouse models of disease.