Beta-Nicotinamide adenine dinucleotide ( b -NAD) mediated signaling cascades protects and repairs endothelial cell barrier The goal of this Project is to characterize the ?-NAD-activated signaling cascades which protect the endothelial cell barrier dysfunction mediated by bacterial toxins and inflammatory agents.
PI : Umapathy N Siddaramappa $25,000 (09/01/09-08/31/2010) Pulmonary Endothelial Cell Barrier Protection by Purinoceptors in Acute Lung Injury The goal of this project is to characterize the purinoceptor-induced endothelial cell barrier enhancement in lung microvasculature.
The Role of Endothelin-1 in Sickle Cell disease - Hemoglobinopathy Translation Research Skills Development Core (HTRC). 1U01 HL117684-01, Kutlas (PI/PD) 4/1/2013-3/31/2018, NIH/H+NHLBI.