Ruth Caldwell

Professor

Ruth Caldwell

Professor

Academic Appointment(s)

Medical College of Georgia
Department of Cellular Biology and Anatomy

Bio

I am a founding member of the Vascular Biology Center and the Vision Discovery Institute and VA Career Scientist. I have published over 140 peer reviewed articles and serve on numerous national review panels. My research is supported by grants from the NIH, VA and AHA. Our current focus is on the potential the urea cycle enzyme arginase as therapeutic target for diabetic retinopathy and other forms of ischemic retinopathy.

  • (706) 721-6145
  • CB 3209A

Education

  • Ph.D., Biopsychology. University of Memphis (The), 1979

  • MS, BioPsych University of Memphis (The), 1976

  • BA, Math, General Agnes Scott College, 1964

Awards & Honors

  • VA Career Scientist 2015

  • Fellow of the AHA 2014

  • Excellence in Research Award 2012

  • Excellence in Research Award 2009

Courses Taught Most Recent Academic Year

  • VBIO 9300

    Research in Vascular Bio
  • VBIO 9010

    Seminar in Vascular Bio
  • VBIO 9020

    Vascular Biology Journal Club

Teaching Interests

Vascular Biology, Retinal Cell Biology

Scholarship

Selected Recent Publications

  • Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury., 2016
    Journal Article, Academic Journal
  • Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy., 2016
    Journal Article, Academic Journal
  • Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model., 2016
    Journal Article, Academic Journal
  • Neuroprotective effect of water-dispersible hesperetin in retinal ischemia reperfusion injury., 2016
    Journal Article, Academic Journal
  • Angiotensin II limits NO production by upregulating arginase through a p38 MAPK-ATF-2 pathway, 2015
    Journal Article, Academic Journal

Research Interests

The current focus of her group’s research is on the potential of the superoxide generating enzyme NADPH oxidase and the urea cycle enzyme arginase as therapeutic targets for diabetic retinopathy and other forms of ischemic retinopathy.

Department Service

  • VBC Search Committee 2016 - Present

    Role: Committee Member

Professional Service

  • AHA/Vascular biology review group/reviewer 2013 - Present

    Role: Reviewer
  • VA IACUC 2010 - Present

    Role: Chairperson
  • NIH National Eye Institute/Study Section/Review group member 2012 - 2016

    Role: Reviewer