Bobby Thomas

Associate Professor

Bobby Thomas

Associate Professor

Academic Appointment(s)

Medical College of Georgia
Department of Pharmacology and Toxicology

The Graduate School
Department of Graduate Studies

Bio

I received my PhD from the Indian Institute of Chemical Biology , Kolkata, India, where I studied the role of nitric oxide and hydroxyl radicals in neurodegeneration as it relates to Parkinson's disease. Subsequently, I joined the laboratory of Dr. Ted Dawson at Johns Hopkins University as a postdoctoral fellow in 2002, where I investigated gene-environment interaction in familial pre-clinical models of Parkinson's disease. Prior to joining the Medical College of Georgia, at Augusta University, I was an assistant professor in the Department of Neurology and Neuroscience at Weill Medical College of Cornell University New York from 2008-2012.

  • (706) 721-6356
  • CB 3618

Education

  • Ph.D., Neurology Jadavpur University, 2002

  • MS, Zoology/Animal Bio Banaras Hindu Univ, 1996

  • BS, Zoology/Animal Bio St. Berchman's College, 1994

Awards & Honors

  • Associate Faculty Member in Neurobiology of Disease F1000, 2009

  • Börje Uvnäs Award in Pharmacology 2002

  • Young Investigator Award RIKEN Brain Science Institute Japan, 2002

  • S.S. Parmar Research Award Indian Academy of Neurosciences, 1998

Courses Taught Most Recent Academic Year

  • MEDI 5210

    Mod 1: Fundamentals
  • MEDI 5236

    Mod 3: Central Nervous System
  • PHRM 8042

    Pharmacology & Therapeutics I
  • PHRM 9020

    Seminar in Pharmacology
  • MEDI 5244

    Mod 7: Endocrine/Reproductive
  • VBIO 8130

    Modern Drug Discovery/Developm

Teaching Interests

Movement disorders, Neuropharmacology, Drug Discovery, Neuroscience

Scholarship

Selected Recent Publications

  • Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease., 2016
    Journal Article, Academic Journal
  • The status of Nrf2-based therapeutics: current perspectives and future prospects., 2016
    Journal Article, Academic Journal
  • Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease., 2016
    Journal Article, Academic Journal
  • Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity, 2014
    Journal Article, Academic Journal
  • Upregulation of GPR109A in Parkinson’s disease, 2014
    Journal Article, Academic Journal

Research Interests

The major interest of our laboratory is to study molecular mechanisms of neurodegeneration induced by genetic mutations, environmental toxicants and gene-environment interactions in Parkinson’s disease with a primary focus on mitochondrial dysfunction and stress signaling pathways involving oxidative stress and neuroinflammation. Our ultimate goal is to utilize this mechanistic knowledge to develop tangible neuroprotective therapies for Parkinson's disease and perhaps other neurodegenerative disorders.

College Service

  • Strategic Planning Committee, Medical College of Georgia 2013 - 2014

    Role: Committee Member

University Service

  • Institutional Biosafety Committee 2014 - Present

    Role: Committee Member

Professional Service

  • ZNS1 SRB-A(11) Special Emphasis Panel (SEP) Project Grant proposals (P01) 2017 - Present

    Role: Reviewer
  • ZRG1 F03B-E 20 Biophysical, Physiological, Pharmacological and Bioengineering Neuroscience Fellowship 2016 - Present

    Role: Reviewer, Ad Hoc Reviewer
  • Medical Research Council of United Kingdom 2013 - Present

    Role: Reviewer
  • Neural Oxidative Metabolism and Death Study Section (NIH) 2013 - Present

    Role: Reviewer
  • Parkinson’s Disease Society of United Kingdom 2013 - Present

    Role: Reviewer