Cardiovascular diseases are the leading cause of death in the United States. Understanding the basic and pathological mechanisms underlying cardiovascular disease and searching new ways to prevent and treat cardiovascular disease is a major focus of the Department of Physiology. Faculty in the department study the cardiovascular system from multiple perspectives. The Department offers advanced an Cardiovascular Physiology and Pharmacology course.
Regents' Professor Dr. R. Clinton Webb directs a NIH-funded Program Project Grant examining the role of inflammation in cardiovascular disease. His laboratory also has a long-term interest in the mechanisms of vascular smooth muscle reactivity, including erectile dysfunction.
Dr. Michael Brands: Integrative cardio-renal physiology in diabetes and inflammation.
Dr. Paul O'Connor: Regulation of kidney function and how disruptions in these pathways can lead to disease.
Dr. David Stepp (VBC): Cardiovascular dysfunction in obesity.
Dr. Jennifer Sullivan: Molecular mechanisms regulating blood pressure in males and females under both physiological and pathophysiological conditions, including hypertension.
Dr. Mong Wang: Eicosanoids in the regulation of renal function and blood pressure.
Dr. Clinton Webb: Hypertension and sexual dysfunction.Above: Diabetes promotes excessive yet immature new vessel formation in the brain. Both the number of collaterals (shown as red and yellow arrows) on the surface of the brain as well as the vascular density within the brain parenchyma (green dye) are increased in diabetes.