Yao Liang Tang

Professor

Yao Liang Tang

Professor

Academic Appointment(s)

Medical College of Georgia
Department of Medicine: Cardiology

Medical College of Georgia
Department of Vascular Biology Center

The Graduate School

Bio

I got my MD in 1993, and Ph.D in 2002, I got my postdoctoral training in Dr. M. Ian Phillips's lab in University of Florida and University of South Florida, I got my 1st faculty position in University of South Florida in 2004, I was promoted to Associate Professor in 2008 in Keck Graduate Institute, and then recruited to University of Cincinnati as tenure track associate professor in 2009, and then recruited to Medical College of Georgia, GRU in 2013. My lab is focused on stem cell biology and epigenetics.

  • (706) 721-8467
  • CB 3303A

Education

  • Ph.D., Biomedical Sciences, General Fudan Univ, 2002

  • MD, Medicine Shanghai Jiao Tong Univ, 1993

Certifications

  • Research Administration Volunteer Recognition Award American Heart Association, 2015

  • FELLOW of American Heart Association (FAHA) American Heart Association, 2012

Awards & Honors

  • 2017 Clinical Science Research Award Medical College of Georgia, Augusta University, 2017

  • Research Administration Volunteer Recognition Award American Heart Association, 2015

  • FELLOW of American Heart Association (FAHA 2012

  • Annual Faculty Research Award Keck Graduate Institute, 2007

  • Dr. Jeff Isner Young Investigator Award (Winner) Massachusetts General Hospital, Cardiovascular Cell and Gene Therapy Conference, 2004

Courses Taught Most Recent Academic Year

  • VBIO 8020

    New Frontiers in Vasc Bio
  • VBIO 8010

    Methods in Cardiovascular Rese

Teaching Interests

course about stem cells and exosomes

Scholarship

Selected Recent Publications

  • Identification of critical molecular pathways involved in exosome-mediated improvement of cardiac function in a mouse model of muscular dystrophy, 2020
    Journal Article, Academic Journal
  • Imaging and Tracking Stem Cell Engraftment in Ischemic Hearts by Near-Infrared Fluorescent Protein (iRFP) Labeling, 2020
    Book, Chapter in Scholarly Book-New
  • Effective restoration of dystrophin expression in iPSC Mdx-derived muscle progenitor cells using the CRISPR/Cas9 system and homology-directed repair technology, 2020
    Journal Article, Academic Journal
  • The Small GTPases Rab27b Regulates Mitochondrial Fatty Acid Oxidative Metabolism of Cardiac Mesenchymal Stem Cells, 2020
    Journal Article, Academic Journal
  • . Enhancer of Zeste Homolog 2 (EZH2) regulates adipocyte lipid metabolism independent of adipogenic differentiation: role of apolipoprotein E. , 2019
    Journal Article, Academic Journal

Research Interests

My primary research goals are to identify the molecular mechanisms of stem cell mediated cardiovascular protection and regeneration. More specifically, we are interested in (1) cross talking between HIF-1α and Notch signaling in homing, survival, and differentiation of stem cells; (2) exosomes-mediated survival signaling in stem cell mediated cardio protection; (3) the regulation of small non-coding RNA (microRNA) and long non-coding RNA (LncRNA) in stem cells; (4) cardiac differentiation of human induced pluripotent stem cells; (4) role of HDAC11 in cardiovascular disease. We found that hypoxic preconditioning enhances paracrine effects of CPC transplantation and improves heart function via angiogenesis and cardiovascular lineage differentiation. I have 16-year’s interdisciplinary research experience in mouse/rat model of myocardial ischemia/reperfusion, mouse cardiovascular physiology, mouse vascular injury model, stem cell biology, molecular biology and histology.

College Service

  • Institutional the Human Stem Cell Research Committee 2018 - Present

    Role: Committee Member
  • Institutional Chemical Safety Committee (ICC) 2016 - Present

    Role: Committee Member

University Service

  • Institutional Chemical Safety Committee (ICC) 2016 - Present

    Role: Committee Member

Professional Service

  • AHA Fellowship 2021 - Present

    Role: Reviewer, Grant Proposal
  • CDMRP Duchenne Muscular Dystrophy 2021 - Present

    Role: Reviewer, Grant Proposal
  • NIH: MPPA 2021 - Present

    Role: Reviewer, Grant Proposal
  • Florida Department of Health James and Esther King Research Program 2020 - Present

    Role: Reviewer, Grant Proposal
  • NIH-CCHF 2020 - Present

    Role: Reviewer, Grant Proposal

Public Service

  • Society for Chinese-American Professors & Scientists (SoCAPS) 2012 - 2013

    Role: Officer, Treasurer