Qin Wang
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Neuroscience and Regenerative Medicine
Medical College of Georgia
Department of Center for Biotechnology and Genomic Medicine
The Graduate School
Education
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AMD, Microbiology and Immunology
Chinese Academy of Preventive, 1995
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MB, Medicine
Beijing Medical College, 1992
Awards & Honors
Courses Taught Most Recent Academic Year
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NURO 9210
Inv of a Problem in Neuro
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NURO 8082
Neuroscience II
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BIOM 8060
Intro to Research II
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BIOM 8080
Neuroscience I
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PSIO 7410
Research
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ANAT 9020
Seminar in Cell Bio/Anatomy
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CURS 2990
Undergrad Research I
Scholarship
Selected Recent Publications
- Activation of a novel α(2A)AR-spinophilin-cofilin axis determines the effect of α(2) adrenergic drugs on fear memory reconsolidation., 2022
Journal Article, Academic Journal
- Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice., 2022
Journal Article, Academic Journal
- Differential requirement for DICER1 activity during the development of mitral and tricuspid valves., 2022
Journal Article, Academic Journal
- A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer's model., 2022
Journal Article, Academic Journal
- Self-paced five-choice serial reaction time-task for mouse behavior testing, 2022
Journal Article, Academic Journal
Research Interests
Dr. Qin Wang's research interests revolve around investigating cell surface receptor signaling and neuropharmacology in the context of brain physiology and disease pathology. Her laboratory employs state-of-the-art techniques, including CRISPR editing, multiomic analysis, super-resolution imaging, pharmacological and behavioral approaches, as well as humanized animal models, human postmortem tissues, and iPSC-derived brain cells, to elucidate the molecular and cellular mechanisms underlying Alzheimer's disease (AD) and complex behaviors. Furthermore, the lab explores the therapeutic potential of targeting these mechanisms for disease treatment, with the ultimate goal of translating their fundamental discoveries into novel clinical applications. One of the primary focuses of Dr. Wang's lab is AD, a multifaceted disease that involves numerous genetic and environmental factors. Her lab employs a multifaceted approach to address this complexity, with a particular emphasis on the following areas: 1) exploring the contribution of noradrenergic dysfunction to AD pathogenesis; 2) investigating alterations in endosomal trafficking in AD and the interactions between AD risk factors; 3) elucidating the role of astrocytic signaling and reactivity in AD progression; 4) examining the relationship between AD risk and cancer therapies, as well as congenital heart diseases; 5) developing treatments for AD by targeting neuronal hyperexcitability.
Department Service
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10x genomics core
2022 - 2023
Role: Other
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junior faculty mentoring
2022 - 2023
Role: Committee Member
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New faculty recruitment
2022 - 2023
Role: Committee Member
University Service
Professional Service
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NIH study section, NCATS special emphasis panel
2023 - Present
Role: Reviewer, Ad Hoc Reviewer
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American Society for Pharmacology and Experimental Therapeutics, Neuropharmacology executive committee
2022 - Present
Role: Committee Member
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Brain Science
2022 - Present
Role: Editorial Review Board Member
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Frontiers in Behavioral Neuroscience
2022 - Present
Role: Editorial Review Board Member
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Frontiers in Neuroscience, Neurodegeneration.
2021 - Present
Role: Editor, Associate Editor