Jan van Riggelen

Assistant Professor

Jan van Riggelen

Assistant Professor

Academic Appointment(s)

Medical College of Georgia
Department of Biochemistry and Molecular Biology

The Graduate School

Bio

Dr. van Riggelen earned his Ph.D. (2005) from the German Cancer Research Center and Ruprecht-Karls University of Heidelberg, Germany, followed by a postdoctoral fellowship at Stanford University.

Education

  • Ph.D., Biology/Biological Sciences, G University of Heidelberg, 2005

  • DIP, Molecular Biology Ruprecht-Karls-Universitat Hei, 2000

Awards & Honors

  • Lymphoma Research Foundation Postdoctoral Fellwoship Lymphoma Research Foundation, 2006

Courses Taught Most Recent Academic Year

  • BCMB 8201

    Cur Topics & Tech in MB
  • BIOM 8215

    Fundamentals of Oncology I
  • BCMB 9300

    Research
  • BCMB 9010

    Seminar in BMB
  • BIOM 8021

    Biochem & Gene Regulation
  • BCMB 8340

    Elements of Scientific Pres
  • MEDI 5150

    Mod 1: Cell & Molecular Basis
  • BCMB 9210

    Investigation of Problem

Teaching Interests

Dr. van Riggelen is committed to excellence in teaching medical and graduate school courses. He serves as instructor for Cellular and Molecular Basis of Medicine (CMBM), Fundamentals of Oncology (COGS 8215), Current topics and techniques in Molecular Biology (COGS 82101) and as instructor and course director for Biochemistry and Gene Regulation (COGS 8021).

Scholarship

Selected Recent Publications

  • p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia., 2015
    Journal Article, Academic Journal
  • High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation, 2012
    Journal Article, Academic Journal
  • Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction, 2011
    Journal Article, Academic Journal
  • Myc and a Cdk2 senescence switch, 2010
    Journal Article, Academic Journal
  • MYC as a regulator of ribosome biogenesis and protein synthesis, 2010
    Journal Article, Academic Journal

Research Interests

Dr. van Riggelen’s laboratory studies the epigenetic aspect of self-renewal and cellular differentiation in cancer using cell and molecular biology approaches. In particular, his team is interested in how the functional properties of transcription factors that determine cell fate are dependent on the epigenetic state of the cell. Dr. van Riggelen’s research focuses on leukemia and lymphoma.

Department Service

  • BMB Faculty Recruitment Committee 2015 - Present

    Role: Committee Member