Amany Tawfik

Associate Professor

Amany Tawfik

Associate Professor

Academic Appointment(s)

Dental College of Georgia
Department of Oral Biology and Diagnostic Sciences

Medical College of Georgia
Department of Culver Vision Discovery Inst

Medical College of Georgia
Department of Pharmacology and Toxicology

Medical College of Georgia
Department of Cellular Biology and Anatomy

The Graduate School

Bio

Dr. Tawfik’s overarching research interests revolve around nutritional deficiencies, specifically folic acid and vitamin B12, and their relationship with amino acid homocysteine in the impairment of vision. She uses basic research techniques to enhance the understanding of how elevated levels of homocysteine contributes to the development and progression of diabetic retinopathy (DR) and age-related macular degeneration (AMD), the most common causes of blindness worldwide. Over the last 10 years, her research has led to the now widely accepted notion which states that homocysteine, serves as a possible biomarker/risk factor for the development/progression of DR and AMD

  • (706) 721-2582
  • CB 2603

Education

  • MD, Medicine Mansoura University, 1992

Awards & Honors

  • P30 EY031631 (Sylvia Smith) , Tawfik co-director NEI, NIH, 2020

  • T35 AG067577 (Bollag) “Program for Aging Research in the Summer (PARIS)” NIH, 2020

  • NIH, R01 National Institute of Health, Office of the Director/NIH/ Pharmacology , 2019

  • NIH R01 Grant, Tawfik, 1 R01 EY029751-01 – NEI00072 NEI-NIH, 2019

  • 1RO1EY028714-01A1 Bartoli (PI) National Institute of Health, NIH/ National Eye Institute, Ophthalmology, 2018

Courses Taught Most Recent Academic Year

  • BMBS 5302

    Bioclinical Seminar II
  • BMBS 5504

    Bioclinical Seminar IV
  • BMCR 5301

    Cardiovascular & Renal Systems
  • BMGH 5301

    Gastrointestinal & Hepatobilia
  • BMMS 5301

    Integ & Musculo Sys I
  • OBMP 9100

    Journal Club in Oral Biology
  • BMNN 5101

    Nervous SyS & Neuroscience I
  • BMRS 5301

    Respiratory System
  • BMBS 5201

    Bioclinical Seminar I
  • BMBS 5403

    Bioclinical Seminar III
  • BMCC 5201

    Craniofacial Complex
  • OBMP 9010

    Grad Oral Bio Seminar

Teaching Interests

I have contributed to didactic and lab teaching in various anatomy courses. In addition I have directed 2 journal club courses, contributed to teaching in DBIO5002 and the Bioclinical Seminar.
I also supervise a doctoral student and postdoctoral Fellow.

Scholarship

Selected Recent Publications

  • Publication Preview Source N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood–retinal barrier dysfunction, 2020
    Cited Research
  • Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche, 2020
    Cited Research
  • A novel interaction between soluble epoxide hydrolase and the AT1 receptor in retinal microvascular damage, 2020
    Cited Research
  • Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction, 2020
    Cited Research
  • Homocysteine; a Potential Biomarker and Therapeutic Target for Diabetic Retinopathy, 2019
    Cited Research

Research Interests

My research is focusing on studying the impact of metabolic disorders on retinal vasculature. In particular the increased levels of amino acid homocysteine and its role in inducing Blood retinal barrier dysfunction. Elucidating mechanisms of homocysteine mediated changes in Blood retinal barrier could lead to the development of treatments for retinal microvascular dysfunction in diseases associated with increased level of homocysteine, such as diabetic retinopathy and age related macular degeneration.

Department Service

  • 2019 - Present

    Role: Other

College Service

  • Research Advisory Committee 2019 - 2021

    Role: Committee Member
  • Student Affairs Committee 2019 - 2021

    Role: Committee Member

University Service

  • University Curriculum and Academic Policies Committee 2020 - 2022

    Role: Committee Member
  • Community Service Committee 2019 - 2021

    Role: Attendee, Meeting

Professional Service

  • Year 2019 - 2020

    Role: Reviewer, Grant Proposal
  • American Heart Association (AHA) 2019 - 2020

    Role: Member
  • The American Diabetes Association 2019 - 2020

    Role: Member
  • National Aeronautics and Space Administration Johnson Space Center Human Exploration and Operations Mission Directorate Human Research Program (NASA), 2019 - 2019

    Role: Reviewer, Grant Proposal
  • Journal of Clinical Medicine 2019 - 2019

    Role: Reviewer

Public Service

  • Food pantry of Islamic Society of Augusta (ISA) 2017 - Present

    Role: Attendee, Meeting
  • American Heart Association (AHA) 2018 - 2018

    Role: Member