Ali Arbab
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Biochemistry and Molecular Biology
Medical College of Georgia
Department of Georgia Cancer Center
Administration
Department of The Graduate School
Bio
I have 35 years of experience in imaging science, involving MRI, SPECT, CT, ultrasound, and optical imaging modalities. My laboratory is working on targeting the tumor micro-environment of glioblastoma and breast cancers using different engineered exosomes and drug-loaded nano-capsules. We are also working with stroke models to improve recovery using engineered exosomes.
Education
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Ph.D., Medical Scientist.
Yamanashi Medical University, 1998
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MD, Medicine
University of Dhaka, 1988
Awards & Honors
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Grant Reviewer
The National Institutes of Health, 2020
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Grant reviewer
California Institute of Regenerative Medicine, 2017
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Travel Award
Radiological Society of North America (RSNA), 2008
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Fellows Award for Research Excellence (FARE)
The National Institutes of Health, 2003
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Asia-Oceania Young Investigator’s Award
Japanese Society of Nuclear Medicine, 1999
Courses Taught Most Recent Academic Year
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BIOM 8230
Biology of Proteins in Disease
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BCMB 8201
Cur Topics & Tech in MB
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BCMB 9010
Seminar in BMB
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CURS 2990
Undergrad Research I
Teaching Interests
Tumor neovascularization, Biomedical Imaging,Tumor micro-environment and possible effect after chemotherapy, engineered exosomes in pathophysiology
Scholarship
Selected Recent Publications
- Single episode of moderate to severe traumatic brain injury leads to chronic neurological deficits and Alzheimer’s-like pathological dementia, 2024
Journal Article, Academic Journal
- Effects of low-intensity pulsed focal ultrasound-mediated delivery of endothelial progenitor-derived exosomes in tMCAo stroke, 2024
Journal Article, Academic Journal
- Isolation and immunosuppressive functions of myeloid-derived suppressor cell-derived exosomes, 2024
Journal Article, Academic Journal
- Experimental study of processing of PCL (polycaprolactone)-peptides nanoparticles and its biodistribution analysis for drug delivery system, 2024
Journal Article, Academic Journal
- Altering biomolecular condensates as a potential mechanism that mediates cannabidiol effect on glioblastoma, 2024
Journal Article, Academic Journal
Research Interests
> Generation of engineered exosomes to initiate ADCC of targeted cells by NK cells.
> Generation of engineered exosomes to target dying neurons in stroke
> Ultrasound-mediated delivery of exosomes to the stroke area to enhance the better outcome
> Understanding the mechanisms of resistance to antiangiogenic treatment in solid tumors.
> Targeting arachidonic acid metabolites for the treatment of solid tumors.
>Tumor cell-secreted exosomes in modulating tumor micro-environment and niche for distal metastasis.
> Generation of tissue-specific MRI and SPECT contrast agents and drug delivery systems (nano-particles).
> Understand the mechanisms of GVHD to delay it by targeting myeloid cells.
Department Service
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Small animal core advisory committee
2020 - 2025
Role: Committee Member
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Director 3T human MRI core
2023 - 2025
Role: Other
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GCC proteomics core
2021 - 2023
Role: Committee Member
University Service
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PT committee of DCG
2023 - Present
Role: Committee Member
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ARAC
2021 - Present
Role: Committee Member
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Mock Study Section
2019 - 2020
Role: Administrative Assignment, Other
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Steering Committee
2019 - 2020
Role: Committee Member
Professional Service
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NIH study panel
2016 - Present
Role: Reviewer, Grant Proposal
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CIRM
2004 - Present
Role: Member
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Scientific Journals
- 2020
Role: Reviewer
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Various scientific journals
- 2020
Role: Editorial Review Board Member
