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Ali Arbab

Professor

Ali Arbab

Professor

Academic Appointment(s)

Medical College of Georgia
Department of Biochemistry and Molecular Biology

Medical College of Georgia
Department of Georgia Cancer Center

The Graduate School

Bio

I have 32 years of experience in imaging science, involving MRI, SPECT, CT, ultrasound, and optical imaging modalities. My laboratory is working on targeting the tumor microenvironment of GBM and breast cancers using different engineered exosomes and drug-loaded nanocapsules.

Education

  • Ph.D., Medical Scientist. Yamanashi Medical University, 1998

  • MD, Medicine University of Dhaka, 1988

Awards & Honors

  • Grant Reviewer The National Institutes of Health, 2020

  • Grant reviewer California Institute of Regenerative Medicine, 2017

  • Travel Award Radiological Society of North America (RSNA), 2008

  • Fellows Award for Research Excellence (FARE) The National Institutes of Health, 2003

  • Asia-Oceania Young Investigator’s Award Japanese Society of Nuclear Medicine, 1999

Courses Taught Most Recent Academic Year

  • BCMB 9300

    Research

  • BCMB 8201

    Cur Topics & Tech in MB

  • PHRM 5003

    Pharmacology Tutorial

  • BCMB 8340

    Elements of Scientific Pres

  • BCMB 9210

    Investigation of Problem

Teaching Interests

Tumor neovascularization.
Biomedical Imaging
Tumor microenvironment

Scholarship

Selected Recent Publications

  • Pulsed Focal Ultrasound as a Non-Invasive Method to Deliver Exosomes in the Brain/Stroke., 2021
    Journal Article, Academic Journal
  • Proteomic Characterization, Biodistribution, and Functional Studies of Immune-Therapeutic Exosomes: Implications for Inflammatory Lung Diseases., 2021
    Journal Article, Academic Journal
  • Critical immunosuppressive effect of MDSC‑derived exosomes in the tumor microenvironment., 2021
    Journal Article, Academic Journal
  • Changes in the tumor microenvironment and outcome for TME-targeting therapy in glioblastoma: A pilot study., 2021
    Journal Article, Academic Journal
  • Stroke promotes the development of brain atrophy and delayed cell death in hypertensive rats., 2020
    Journal Article, Academic Journal

Research Interests

> Generation of engineered exosomes to initiate ADCC of targeted cells by NK cells.
> Ultrasound mediated delivery of exosomes
> Understanding the mechanisms of resistance to antiangiogenic treatment in solid tumors.
> Targeting arachidonic acid metabolites for the treatment of solid tumors.
>Tumor cell-secreted exosomes in modulating tumor microenvironment and niche for distal metastasis.
> Generation of tissue-specific MRI and SPECT contrast agents and drug delivery systems (nanoparticles).

Department Service

  • GCC proteomics core 2021 - Present

    Role: Committee Member

  • Small animal core advisory committee 2021 - Present

    Role: Committee Member

University Service

  • ARAC 2021 - Present

    Role: Committee Member

  • Mock Study Section 2019 - 2020

    Role: Administrative Assignment, Other

  • Steering Committee 2019 - 2020

    Role: Committee Member

Professional Service

  • NIH study panel 2016 - Present

    Role: Reviewer, Grant Proposal

  • CIRM 2004 - Present

    Role: Member

  • Scientific Journals - 2020

    Role: Reviewer

  • Various scientific journals - 2020

    Role: Editorial Review Board Member