Skip to main contentBack to Top

Pharmacology and Toxicology was established as a department at the Medical College of Georgia in 1943.

 

Originally developed to discover how remedies and poisons effected man, modern pharmacology lays the groundwork to discover and develop future generations of therapeutics. Pharmacology's scope has broadened to include: computer-assisted drug design; genetic screens; protein engineering; and new drug-delivery vehicles like viruses and artificial cells.

 The department's history of accomplishments include the discovery of the adrenergic receptor subtypes-alpha and beta which led to developing several drugs used to treat cardiovascular disease. Cardiovascular and neuroscience studies are the focuses of the department's research programs.

Raymond P. Ahlquist, working in this Department, first defined α and β adrenergic receptors in 1948. This discovery eventually led to the development of “β blocker” drugs for hypertension and heart disease.

β adrenergic receptors (blue) clustered into artificial microdomains on the surface of a living COS7 cell (red).

β adrenergic receptors (blue) clustered into artificial microdomains on the surface of a living COS7 cell (red).  

Contact Us

Department of Pharmacology & Toxicology

Health Sciences Campus

Carl T. Sanders R & E Building

706-721-2345

Ashley Davis

RM 3530

Cardiovascular & Neuroscience  Research

Learn more about research studies in Cardiovascular & Neuroscience Research.

Core Labs

Cores, or Shared Research Resources are institutionally funded and supported research centers that are dedicated to meeting scientists’ research needs. Augusta University's Cores Laboratories and or Shared Research Resources are supported by the Senior Vice President for Research.

Facilities

Learn more about the Pharmacology Facilities.

Department Highlights

  • Research in the areas of cardiac, vascular, and pulmonary disease, schizophrenia, learning and memory, neuroprotection and drug abuse.


  • Experimental approaches range from the gene to whole animal.

Pharmacology & Toxicology News

Two men in white coats in lab

Novel treatment target for heart disease found in the blood vessel wall

A molecule of RNA called CARMN has been found in abundance in the healthy smooth muscle cells that help give our blood vessels strength and flexibility, and distinctly decreased in vascular diseases like atherosclerosis, a major cause of heart attack and stroke, scientists report.

Three people in white coats (one woman, two men) stand in hallway

Gene that aids cancer cell proliferation is new target for deadly pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

Two researchers, a man on the left and woman on the right, stand in a lab with white coats on

Copper transporter potential new treatment target for cardiovascular disease

An internal transporter that enables us to use the copper we consume in foods like shellfish and nuts to enable a host of vital body functions also has the essential role of protecting the receptor that enables us to grow new blood vessels when ours become diseased, Medical College of Georgia scientists report.

doctor in lab

Finding its way to the top: How a cell surface receptor reaches its destination

Dr. Guangyu Wu is dissecting the molecular homing that enables a nascent protein to ultimately find its way to the surface of a cell as a mature receptor type that helps us taste, smell and even regulate our mood and immunity.

 MORE PHARMACOLOGY & TOXICOLOGY NEWS