Huabo Su

Assistant Professor

Huabo Su

Assistant Professor

Academic Appointment(s)

Medical College of Georgia
Department of Pharmacology and Toxicology

The Graduate School

Education

  • Ph.D., Biochemistry and Molecular Bio Fudan University, 2004

  • MD, Molecular Bio Guangxi University, 2001

  • BS, Bio, General Guangxi Normal University, 1997

Awards & Honors

  • Outstanding Junior Faculty Award of the 2nd ACRE/APS symposium 2015

  • New Investigator Travel Award of the Basic Cardiovascular Sciences Conference American Heart Association, 2008

Courses Taught Most Recent Academic Year

  • VBIO 9300

    Research in Vascular Bio
  • HONR 4000H

    Honors Thesis
  • VBIO 9210

    Investigation of a Prob
  • VBIO 9010

    Seminar in Vascular Bio
  • VBIO 9020

    Vascular Biology Journal Club
  • COGS 8120

    Cardiovas Physio & Pharma

Scholarship

Selected Recent Publications

  • $\beta$-arrestin-biased agonism of $\beta$-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling, 2018
    Journal Article, Academic Journal
  • A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes, 2018
    Journal Article, Academic Journal
  • Neddylation mediates ventricular chamber maturation through repression of Hippo signaling, 2018
    Journal Article, Academic Journal
  • Cardiac Lipid Metabolism and Contractile Function in Type 2 Berardinelli-Seip Congenital Lipodystrophy (BSCL2) Disease, 2017
    Conference Proceeding
  • Characterization of mice carrying a conditional TEAD1 allele, 2017
    Journal Article, Academic Journal

Research Interests

My research focuses on understanding the biological function of ubiquitin-like protein modifiers including NEDD8 and Ufm1 in cardiomyocytes, with an ultimate goal to elucidate the molecular mechanisms of heart failure and to search for novel therapeutic measures. We are particularly interested in addressing three major questions: are neddylation and ufmylation essential for cardiac function under physiological and pathological conditions? How does each modification control different cellular processes in cardiomyocyte? What proteins are targeted by NEDD8 or Ufm1 in cardiomyocytes, and how does such modification regulate the molecular function of the target? We employ in vitro molecular and cellular biology approaches, proteomics approach and the state-of-the-art in vivo mouse physiology analyses to address these questions.

Department Service

  • Vascular Biology Center Journal Club 2015 - Present

    Role: Other