HongYan Liu

Assistant Professor

HongYan Liu

Assistant Professor

Academic Appointment(s)

Medical College of Georgia
Department of Biochemistry and Molecular Biology

The Graduate School
Department of Graduate Studies

  • (706) 721-7149
  • CA II 4096


  • Ph.D., Immunology Norman Bethune University of M, 2000

  • MS, Biochem Jilin University, 1995

  • BS, Biochem Jilin University, 1992

Awards & Honors

  • Prostate Cancer research Program Idea Deveopment Award Department of the ARMY, 2015

Courses Taught Most Recent Academic Year

  • GNMD 8052

    Func Geno & Prote Using Anml M
  • GNMD 8060

    Genomic Medicine Seminar


Selected Recent Publications

  • Bivalent aptamer-dual siRNA chimera is emerging as a new combination therapy, 2017
    Journal Article, Academic Journal
  • Simultaneous targeting of CD44 and EpCAM with a bispecific aptamer effectively inhibits intraperitoneal ovarian cancer growth, 2017
    Journal Article, Academic Journal
  • Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer, 2016
    Journal Article, Professional Journal
  • Solid-phase bioconjugation of heterobifunctional adaptors for versatile assembly of bispecific targeting ligands, 2014
    Journal Article, Academic Journal
  • A Universal protein tag for delivery of SiRNA-Aptamer Chimeras, 2013
    Journal Article, Academic Journal

Research Interests

Our studies focus on developing targeted drugs for cancer therapy and developing ultra-sensitive probes for disease early detection. We are using siRNAs and aptamers to design the novel gene therapeutics which have potential to solve the problems of off-target effect and toxicity of current chemotherapy. We functionalize quantum dot nanoparticles for multiplexed ultrasensitive detection of disease biomarkers

Department Service

  • Graduate student committee 2014 - Present

    Role: Mentor

University Service

  • Augusta University Institutional Chemical Safety Committee 2016 - Present

    Role: Committee Member

Professional Service

  • Scientific Reports 2016 - Present

    Role: Reviewer
  • Oncotarget 2015 - Present

    Role: Reviewer