Guangyu Wu
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Pharmacology and Toxicology
Administration
Department of The Graduate School
Bio
I am a cell biologist studying G protein-coupled receptors and G proteins.
- GUWU@augusta.edu
- (706) 721-0999
- CB 3528
Education
-
Ph.D., Physiology, General
Peking Union Medical College, 1994
-
MD, Medicine
Xuzhou Medical College, 1988
Courses Taught Most Recent Academic Year
-
BIOM 8022
Molecular Cell Biology
-
PHRM 8042
Pharmacology & Therapeutics I
-
PHRM 9020
Seminar in Pharmacology
Teaching Interests
I have over forty years’ experience teaching undergraduate, graduate, and medical students in a variety of topics. My recent primary teaching has been in graduate and medical education on cancer chemotherapy and G protein-coupled receptors (GPCRs).
Scholarship
Selected Recent Publications
- Fibroblast Growth Factor 2 Is Produced By Renal Tubular Cells to Act as a Paracrine Factor in Maladaptive Kidney Repair After Cisplatin Nephrotoxicity., 2023
Journal Article, Academic Journal
- Non-canonical Golgi-compartmentalized Gβγ signaling: mechanisms, functions, and therapeutic targets., 2023
Journal Article, Academic Journal
- Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models., 2023
Journal Article, Academic Journal
- The role of G protein conformation in receptor-G protein selectivity., 2023
Journal Article, Academic Journal
- ATIC-Associated De Novo Purine Synthesis Is Critically Involved in Proliferative Arterial Disease., 2022
Journal Article, Academic Journal
Research Interests
The long-term objective of my research is to understand the molecular mechanisms that govern the intracellular trafficking, signal propagation and pathophysiological functions of GPCRs and G proteins. Our recent work has focused on GPCR maturation processing and G protein bg subunit-mediated signaling in prostate cancer biology.
