Purpose

The Georgia Cancer Center is excited to announce the 2024 RFA for Paceline Awards! Paceline fundraising efforts will support research activities at the Georgia Cancer Center in our mission to reduce the burden of cancer in Georgia and across the globe through superior care, innovation and education. To this effect, we are calling for proposals that further our mission and support our goal to achieve NCI designation.

Eligible research categories include Basic Science, Clinical/Translational, and Population/Health Disparities Research. Each of these categories may be addressed by the following types of projects: PI-Initiated; Early-Career Investigators (Faculty within 7 years of their first time faculty appointment); Multi-PI; and Trainee Mentored Research (for students/fellows/residents in conjunction with a mentor). All awards are intended to generate preliminary data (including that for high-risk, high-reward research) to seed competitive, peer-reviewed, external grant applications, leading to the sustained extramural support needed for NCI designation.

Amount: Top-scoring peer-reviewed projects will be eligible to compete for up to $50,000 or $35,000 (Trainees).

Please note New Paceline Requirement: Donate a minimum (personally or via fund raising) of $200 (Faculty applicants) and $20 (Trainee applicants) by December 31, 2023.

Subject Categories

  • Basic Science: Projects that investigate the etiology of cancer genesis, progression and metastasis or mechanisms of resistance. These studies will generate preliminary data on new  areas of research that will lead to the submission of cancer-focused grant proposals to any NIH branch or other agencies that may support NCI designation.

  • Clinical/Translational Research: These studies help transition a bench discovery into the clinic. Priority will be given to studies that originate from research performed at the Georgia Cancer Center. Collaborations between a laboratory investigator and a clinical investigator are encouraged.

  • Population/Health Disparities Research: These studies aim to understand or to address cancer in underrepresented populations, specifically in minorities as defined by the Office of Management and Budget (OMB): The minority racial and ethnic groups defined by OMB are American Indian or Alaska Native, Asian, Black or African American, and Native Hawaiian or other Pacific Islander. The ethnicity used is Latino or Hispanic. Included are studies that aim to understand healthcare disparities and approaches to overcome them.

Project Types

  • PI-Initiated: This research led by an individual PI will generate preliminary data that will seed sustained extramural support needed for NCI designation. (Maximum budget request $50,000)

  • Early Career Investigator: Faculty at the level of Instructor, Assistant Research Scientist, or Assistant Professor within 7 years of appointment. Funds can be used for travel to one scientific meeting if requested in budget. (Maximum budget request $50,000)

  • Multi-PI Projects: will propose innovative research that requires teams of investigators with complimentary expertise. The goal of this mechanism is to support Multi-PI projects that can help develop projects that will lead to large multi-PI or program project-like grants. These projects require a 200-word description of the complementary expertise and how the project will lead to externally funded Multi-PI projects in the future. Based on a favorable progress report, these projects may be eligible for a second-year extension. (Maximum budget request $50,000)

  • Trainee Mentored Research: These studies are conducted by graduate students, postdoctoral fellows, or. These can be basic, translational, or clinical research. A faculty mentor must be identified for this research, and the awardee and mentor will work closely together in the design and conduct of the study. The work could be either ongoing research of the applicant or new research identified by the mentor where the applicant plays a major role. These grants may cover the following allowable costs, up to a maximum of $35,000: up to 50% of salary support to conduct mentored research, professional development activities, and/or travel to one national meeting to present research.

Proposal Requirements

Project summary (500 words or less), consisting of a brief background to the problem; hypothesis; clear objectives and specific aims that address the problem; what has already been done regarding this problem; approach (research and design); and the significance of the proposed work.

Cover Page (see attached template) including: (PDF)

  • Title of grant
  • Name and title of PI (and Co-PIs, if applicable)
  • Subject Category (basic science research; clinical/translational research; population/health disparities research)
  • Grant type (PI-Initiated; Early-Career Investigator; Multi-PI; or Trainee Mentored Research)
  • Name and title of mentor, if applicable
  • 2023 Paceline Participation (new requirement)
  • Plans for the submission of the resulting data as an external grant application, to include grant type and submission timeline.

 

Research Plan (2 pages or less, margins measuring at least 0.5 inch, 11-point Arial font). The description should include:

  • Background
  • Hypothesis
  • Specific aims
  • Significance
  • Innovation
  • Approach
  • Statistics and rigor
  • A timeline depicting the anticipated progress of the studies within this award

 

References (No page Limit)

Budget and justification of expenditures (No page limit)

Other Attachments

  • NIH Biosketch for all PIs and Mentors
  • Other support
  • Multi-PI justification for Multi-PI proposals: A 200-word description of the complementary expertise and how this project will lead to externally-funded Multi-PI projects in the future
  • Early-Career Investigators: give a timeline of your first faculty appointment
  • Trainee Mentored Research proposals:
  • A 200-word description of the applicant and his/her future goal
  • A letter of support from the Mentor: The letter should state the Mentor’s qualifications, support for the candidate and the mentorship plan related to the proposed project

Eligibility/Criteria

  • PI (and mentor when applicable) must be members of the Georgia Cancer Center.
  • Participation in Paceline (2023; ie, through December 2023): NEW THIS YEAR
    • Faculty-led grant applicants: Minimum commitment to raise/donate $200 to Paceline.
    • Trainee-led grant applicants (students/fellows): Minimum commitment is to raise/donate $20 to Paceline.
  • The research must be cancer-related.
  • Current funding level is irrelevant for the purposes of this award.
  • Preliminary data is preferred but not required; when no preliminary data available, a strong background and description of feasibility of hypothesis is necessary.
  • Funding must not be used for large equipment; PI salary support or travel (except for the Early-Career Investigator and Trainee Mentored Research, as described above); and will be for one year without the possibility of extension (except for the Multi-PI Projects, as described above).
  • Awardees will be required to submit a progress report at the end of the funding cycle (i.e., 1 year after release of funds).
  • Please contact Dr. Lisa Middleton with questions or concerns.

Deadline:

Submit Proposals to Dr. Lisa Middleton, by 11:59 pm, January 31, 2024.