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- Curcuma caesia Derivatives: Chemical Composition and Effects on Somatosensory Responses of Healthy Adults in the S.E. United States
Clinical Trial
Curcuma caesia Derivatives: Chemical Composition and Effects on Somatosensory Responses of Healthy Adults in the S.E. United States
The purpose of this study is to determine if derivatives of Black Turmeric will slow down pain signals sent to the brain. Pain signals are sent to the brain by messengers called neurotransmitters. One neurotransmitter is named substance P. We want to determine whether derivatives of Black Turmeric decrease substance P when the skin is warmed. Additionally, we want to determine if derivatives of Black Turmeric increase the amount of pressure a person can feel before the sensation becomes painful. This is called pain-pressure threshold. We test pain-pressure threshold by pushing against the skin on the forearm with a flat probe using a device called an algometer. Findings from this study may help us reduce the amount of pain felt on the forearm and signals sent to the brain for people with chronic pain.
- Nervous System
- Black Turmeric
- Curcuma Caesia
- Local Thermal Hyperemia
- Pain
- Pain-pressure Threshold
- Substance P
Eligibility Criteria
- Inclusion Criteria: Adults (18 years of age and older) who are generally healthy and able to make their own decisions English speaking Able to lie on their back and rest quietly for up to an hour and a half Exclusion Criteria: A history of trauma or injury to the right arm Taking any prescription medications (including birth control pills)