Selected Publications

Selected Recent Publications

Moskophidis, D., and D. Kioussis (1998). Contribution of virus-specific CD8 + cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model. J. Exp. Med. 188, 223-232.

Price G. E., A.Gaszewska-Mastarlarz, and D. Moskophidis (2000). The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice. J. of Virology 74, 3996-4003.

Price G. E., R. Ou, H. Jiang, L. Huang and D. Moskophidis (2000). Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia. J. Exp. Med. 191, 1853-1867.

Ou R., S. Zhou, L. Huang, and D. Moskophidis. (2001). A critical role for interferon alpha/beta and gamma in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T-cells. J. of Virology 75: 8407-8423.

Huang L., N. Mivechi and D. Moskophidis (2001). Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: Analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 genes. Molecular and Cellular Biology 21: 8575-8591.

Zhou, S., L. Huang., R. Ou, and D. Moskophidis (2002). A critical role for perforin, Fas/FasL, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent infection. J. of Virology 76: 829-840.

Zhang, Y., L. Huang, D. Moskophidis, and N. Mivechi (2002). Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation for stress-inducible Hsp molecular chaperones. J. of Cellular Biochemistry 86:376-393.

Wang G., J. Zhang, D. Moskophidis, and N.F. Mivechi. (2003). Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis 36:48-61.

Zhou, S., R. Ou, L. Huang, G. Price, and D. Moskophidis (2004). Differential tissue-specific regulation of CD8 + T cell mediated immune response during chronic viral infection J. of Virology 78: 3578-3600.

Wang, G., Z. Ying, X. Zing, N. Tu, J. Zhang, M. Phillips, D. Moskophidis, and N. F. Mivechi. (2004). Essential requirement for both hsf1 and hsf2 transcriptional activity in spermatogenesis and male fertility. Genesis 38:66-80.

Min, Jin-Na, Y. Zhang, D. Moskophidis, and N. F. Mivechi. (2004). Unique contribution of heat shock factor 4 as master control gene in lens development and fiber cell differentiation Genesis 40:205-217.

Gronski MA, Boulter JM, Moskophidis D, Nguyen LT, Holmberg K, Elford AR, Deenick EK, Kim HO, Penninger JM, Odermatt B, Gallimore A, Gascoigne NR, Ohashi PS. (2004). TCR affinity and negative regulation limit autoimmunity. Nature Medicine 10:1234-1239.