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The unifying theme of the Tumor Signaling & Angiogenesis program is to build translational clinical trials based on innovative and novel research projects that focus on signaling cascades leading to uncontrolled cell growth and resistance to apoptosis.

The program goals are to identify dysregulated molecular signaling pathways that can be used as cancer-specific targets. Collectively the members of this program work cooperatively to study a variety of kinase targets involved in cancer cell proliferation and progression.

Targets identified in this program can be exploited to develop innovative approaches to cancer prevention and therapy that can be translated into clinical trials. The research into cancer cell signaling incorporates animal models in breast and colon cancer, as well as the pediatric cancer neuroblastoma, to study how specific signaling pathways are involved in the progression of cancer.

Program Members

photo of Ali Arbab, MD, PhD

Ali Arbab, MD, PhD

  • Professor
photo of Han-Fei Ding, PhD

Han-Fei Ding, PhD

  • Professor
photo of Ellen K. LeMosy, MD, PhD

Ellen K. LeMosy, MD, PhD

  • Associate Professor
photo of Honglin Li, PhD

Honglin Li, PhD

  • Associate Professor
photo of Betty Pace, MD

Betty Pace, MD

  • Professor
photo of Daitoku Sakamuro, PhD

Daitoku Sakamuro, PhD

  • Associate Professor
photo of Patricia V. Schoenlein, PhD

Patricia V. Schoenlein, PhD

  • Associate Professor
photo of Muthusamy Thangaraju, PhD

Muthusamy Thangaraju, PhD

  • Associate Professor
photo of Guangyu Wu, PhD

Guangyu Wu, PhD

  • Professor

Cancer Research News

Man in black coat and shirt leans against building

Moore recognized with AACR Minorities in Cancer Research award

Dr. Justin Xavier Moore has been recognized with an American Association for Cancer Research Minorities in Cancer Research award.

Colon Cancer Awareness Month ribbon in front of picture of the Georgia Cancer Center

Oncology professor answers questions regarding National Colon Cancer Awareness Month

"Colon cancer is largely preventable if patients undergo screening tests, like a surveillance colonoscopy starting at 45 years or earlier depending on family history."

photo from article Georgia Cancer Center researcher works to develop new treatment options for liver cancer

Georgia Cancer Center researcher works to develop new treatment options for liver cancer

Despite liver cancer being the third leading cause of cancer deaths worldwide, there are not many treatment options currently available for patients. Dr. Yukai He and his team want to change that.

People standing hold a big check

Paceline donates $330,069 to advance research projects at Georgia Cancer Center

This year’s fundraising total represents a 65% increase since its inaugural event held in May 2019.