Study Description: Researchers have found a link between COPD and heart disease; however, a link is all they have found. This project is a follow up to a previous study we have done in which we found that a single dose of antioxidants and BH4 both improve vascular health in patients with COPD. The purpose of this study is to see if longer use of antioxidants or BH4 sustain the improvements in vascular health in patients with COPD
Principal Investigator: Ryan Harris
Eligibility Criteria: 24 healthy controls that are 18years of age and greater. 24 patients that have been dianosed with Chronic Obstructive Pulmonany Disease
Compensation: Yes, subjects will be compensated.
Compensation Explanation: Subject Payment Patients with COPD who participate in the BH4 protocol (Protocol 1) will be paid a total of $250 U.S. dollars which equates to $50 U.S dollars for each experimental day completed). Patients with COPD who participate in the antioxidant cocktail protocol (Protocol 2) will be paid a total of $250 U.S. dollars which equates to $50 U.S dollars for each experimental day completed). Apparently healthy volunteers will be paid a total of $80 U.S. dollars and will not undergo any treatment. Payment will be made using the Greenphire ClinCard. It works like a bank debit card. We will give you a debit card and each time you receive a payment for participation in this study, the money will be added to the card after each completed visit. You may use this card at any store that accepts credit cards or you can use a bank machine to remove cash. However, there may be fees drawn against the balance of the card for cash withdrawals and inactivity. You will receive letters with additional information on how you can use this card and who to call if you have any questions. Be sure to read these letters, including the cardholder agreement, for details about fees. The debit card system is administered by an outside company. The company, Greenphire, will be given your name and social security number. They will use this information only as part of the payment system. Your information will not be used for any other purposes and will not be given or sold to any other company. Greenphire will not receive any information about your health status or the study in which you are participating. If you are an Augusta University employee, payment will be included in your payroll check. This payment will be subject to Federal and Georgia state withholding taxes as well as FICA tax and will reflect on the W-2 form at calendar year end. Payment received as compensation for participation in research is considered taxable income to the research participant. If payment to an individual exceeds $600 in any one calendar year, Augusta University is required to report this information to the Internal Revenue Service (IRS). Research participant payments to a non-employee of AU exceeding $600 during any calendar year will result in a 1099 (Miscellaneous Income) form being issued to the individual and a copy sent to the IRS.
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