Study Description: Vitamin K is a fat-soluble vitamin found mostly in leafy green vegetables (e.g., spinach, broccoli, kale, and collards) and in soybean oil and canola oil. Vitamin K is necessary for normal blood clotting and may be needed for other activities such as normal glucose metabolism. Understanding the role of vitamin K in glucose metabolism may help develop preventive strategies and early interventions to reduce obesity-related disorders such as type 2 diabetes. The purpose of this study is: a) To determine if taking two capsules daily of vitamin K supplement for eight weeks (two months) can improve markers in blood associated with diabetes risk; b) To understand how factors such as hormones (specific to bone and fat metabolism), body composition, diet, and physical activity may influence vitamin K?s effect on body?s use of glucose (sugar); c) To examine the relationship between insulin resistance, a marker of diabetes risk, and bone strength.
Principal Investigator: Norman Pollock
Eligibility Criteria: good general health age 18 to 65 years no medical condition that would affect study results not using medications or receiving treatment likely to interfere with study evaluation
Compensation: Yes, subjects will be compensated.
Compensation Explanation: Participants will receive (for completing the study measurements and questionnaires): $60 when they complete the study measures at the start of the study. $60 at the end of the study when they complete the study measures again. Payment will be made using a pre-paid debit card. It works like a bank debit card. We will give you a debit card and each time you receive a payment for participation in this study, the money will be added to the card after each completed visit. You may use this card at any store that accepts credit cards or you can use a bank machine to remove cash. However, there may be fees drawn against the balance of the card for cash withdrawals and inactivity. You will receive letters with additional information on how you can use this card and who to call if you have any questions. Be sure to read these letters, including the cardholder agreement, for details about fees. The debit card system is administered by an outside company. The company, Greenphire, will be given your name and social security number. They will use this information only as part of the payment system. Your information will not be used for any other purposes and will not be given or sold to any other company. Greenphire will not receive any information about your health status or the study in which you are participating.
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