Study Description: The purpose of the this study is to look at how a medication, mycophenolate mofetil (MMF), which is an immunosuppressant, effects sodium excretion and blood pressure following a mental stressor. MMF is a drug that has been approved by the Food and Drug Administration (FDA) and is designed to stop/reduce inflammation specifically for organ donor recipients. When we hear the word inflammation, we usually think of redness or swelling. However, stress also causes inflammation. This study is to determine if stopping the stress induced increase in inflammation will prevent sodium retention.
Principal Investigator: Gregory Harshfield
Eligibility Criteria: * African American (male or female) * Ages 18 - 50 - good general health * Not on any prescription medication * Do not have high blood pressure * Not pregnant or breastfeeding
Compensation: Yes, subjects will be compensated.
Compensation Explanation: SUBJECT PAYMENT Payment will be made using a pre-paid debit card. It works like a bank debit card. We will give you a debit card and each time you receive a payment for participation in this study, the money will be added to the card after each completed visit. You may use this card at any store that accepts credit cards or you can use a bank machine to remove cash. However, there may be fees drawn against the balance of the card for cash withdrawals and inactivity. You will receive letters with additional information on how you can use this card and who to call if you have any questions. Be sure to read these letters, including the cardholder agreement, for details about fees. The debit card system is administered by an outside company. The company, Greenphire, will be given your name and social security number. They will use this information only as part of the payment system. Your information will not be used for any other purposes and will not be given or sold to any other company. Greenphire will not receive any information about your health status or the study in which you are participating. For completing the screening visit, which includes all aspects of the screening described above, you will receive $20.00 which will be added to your debit card. For participating in the testing protocol, you will receive $200.00 for both 7
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