Neuromuscular Research

Antibodies in AIDP/CIDP - Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a neurological disorder in which there is progressive (occurring gradually over a period of time) weakness and impaired sensory function in the legs and arms.  Acquired Inflammatory Demyelinating Polyneuropathy (AIDP) is a neurological disorder in which there is an acute (rapid onset) of weakness and impaired sensory function in the legs and arms and often causes respiratory problems. The purpose of the research study is to collect antibodies from patient samples and use them to understand better the prognosis and etiology of inflammatory neuropathy.  

 

Antibodies in Myasthenia Gravis - The purpose of this study is to collect samples from MG patients and to evaluate for Novel antibodies, LRP4 and Agrin. The results from these future studies will allow us to understand new formed MG.

 

Antibodies in Amyotrophic Lateral Sclerosis (ALS) - The purpose of this study is to collect a blood sample from ALS patients to evaluate for the presence of antibodies which might lead to a better understanding of the cause of ALS.

 

A Phase 2 Pharmacodynamic Study of Ezogabine on Neuronal Excitability in Amyotrophic Lateral Sclerosis (ALS) - This research is being done in order to understand more about motor neuron excitability in people who have amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease) compared to people without ALS. We will evaluate Ezogabine (Retigabine) for the efficacy in ALS.

 

Botox Treatment in Adult Patients with Upper Limb Spasticity - The purpose of this study is to investigate how safe and how well BOTOX® (Dose of 300 units and/or 500 units per study treatment compared to placebo) works in the treatment of adults who have experienced a stroke resulting in spasticity in one of their upper limbs, particularly those with shoulder and arm stiffness. Spasticity is a state of increased muscle tone that can cause stiff and awkward movements.